WEEK 1 INTRO

Question 1

Science of dosage form design

➢ Discipline in pharmacy that deals with all the features of the process of turning a new chemical entity into a medication able to be safely and effectively used by patients in the community.

Answer 1

PHARMACEUTICS

Question 2

Is an agent intended for use in the
diagnosis, mitigation, treatment,
cure or prevention of disease in
humans or in other animals. (FDC Act 1938)

Answer 2

DRUG

Question 3

Is the* physical form of a dose of a chemical compound used as a drug
or medication intended for
administration or consumption.
➢ “a form by which drug molecules are delivered to sites of action within the body”

Answer 3

PHARMACEUTICAL DOSAGE FORM

Question 4

Method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or in animals.
➢ Focus on the synthesis of target
therapy.

EXAMPLES:
❖ Transdermal Drug Delivery System
❖ Topical Drug Delivery System

Answer 4

DRUG DELIVERY SYSTEM

Question 5

Is the path by which a drug is brought into contact with the body.
➢ A substance must be transported from the site of entry to the part of the body where its action is desired to
take place.

Answer 5

DRUG DELIVERY ROUTE

Question 6

SELECTION OF THE ROUTE DEPENDS
ON 3 FACTORS:

Answer 6

❖ Effect Desired
❖ Type of Disease
❖ Type of Product

Question 7

under the tongue

Answer 7

Sublingual

Question 8

inhalation through
mouth

Answer 8

Inhalation

Question 9

mouth

Answer 9

ORAL

Question 10

rectum

Answer 10

RECTAL

Question 11

skin (internal
or direct to the system circulation)

Answer 11

TRANSDERMAL PATCH

Question 12

skin (external or outer
layer)

Answer 12

TOPICAL

Question 13

intravenous (IV),
intramuscular (IM), subcutaneous
(SC)

Answer 13

**Parenteral **

Question 14

these are drugs that causes mydriasis (dilation of pupils)

e.,g: epinephrine and phenylephrine

Answer 14

MYDRIATIC DRUGS

Question 15

these are drugs that causes miosis (constriction of the pupils)

e.,g: carbachol

Answer 15

MYOTIC DRUGS

Question 16

induces vomiting

e.,g: cupric sulfate, epicac syrup

Answer 16

EMETICS

Question 17

induce diuresis

e.,g: furosemide

Answer 17

DIURETICS

Question 18

prevents vomiting

e.,g; domperidone, metoclopramide, meclizine

Answer 18

ANTI-EMETICS

Question 19

respiratory tract fluid, it helps thin the secretions in your airway and loosen up mucus.

e.,g: guaifenesin

Answer 19

EXPECTORANTS

Question 20

to stimulate or facilitate evacuation of the bowels

e.,g: bisacodyl (dulcolax)

Answer 20

CATHARTICS/LAXATIVE

Question 21

give an example of transdermal patch

Answer 21

• nitroglycerin patch
• scopolamine patch

nitroglycerin- for angina pectoris
scopolamine- motion sickness

Question 22

what are the most effective routes of
administration?

Answer 22

oral, rectal,
parenteral, topical

Question 23

provide a specific example of a drug classified as an emetic that is used in emergency situations to induce vomiting and help expel poisons from the patient’s system?

Answer 23

Ipecac syrup

Question 24

Provide a specific example of a medication currently available on the market that is formulated as soft gel capsule

Answer 24

Ibuprofen

Question 25

what dosage form is meclizine or Bonamine 25 mg available in? be specific.

Answer 25

Chewable tablet

Question 26

what is the term used to describe the rate at which a drug is taken up and enters the bloodstream after it is administered?

Answer 26

Absorption rate

Question 27

what is the term used to describe the length of time that a drug remains effective and produces its therapeutic effects in the body after administration?

Answer 27

Duration of action