week 1 - cardiac + HTN Flashcards
What is Acute Coronary Syndrome (ACS)?
-prolonged ischemia that is not immediately reversed, which includes:
~NSTEMI
~STEMI
~unstable angina
angina pectoris is chest pain due to what?
myocardial ischemia
what is atheroma AKA plaque?
caps of smooth muscle cells that form over lipid deposits in arterial vessels
-protrude into the lumen of the vessel
-lumen becomes narrowed
-blood flow is obstructed
atherosclerosis is the most common cause of CVD, what is it?
abnormal accumulation of lipid deposits + fibrous tissue in arterial walls + lumen
what is a coronary artery bypass graft (CABG)?
-surgical procedure
-a blood vessel from another part of the body is grafted onto the occluded coronary artery below/ after the occlusion so that blood flow can bypass the block
what are high density lipoproteins (HDL)?
-higher proportion of protein
-a lipid that transports cholesterol to liver for secretion through the bile
-good protein
-benefits the arterial wall
what is ischemia?
insufficient tissue oxygenation/ obstructed blood flow
what are low density lipoproteins (LDL)?
-lower proportion of protein
-a lipid that transports cholesterol to the body tissue
-harmful to the arterial wall
what is metabolic syndrome?
a cluster of metabolic abnormalities that increase risk of cardiovascular disease
-insulin resistance
-obesity
-dyslipidemia/ hyperlipidemia
-hypertension
what is MI?
-heart tissue death
-lack of oxygenated blood flow
what is percutaneous coronary intervention (PCI)?
when a catheter is placed in the coronary artery to reduce blockage
what is percutaneous transluminal coronary angioplasty (PTCA)?
a balloon is inflated in the coronary artery to break an atheroma, open the vessel lumen + improve blood flow
what is a stent?
metal mesh that provides structural support to a coronary vessel to prevent collapse/ closure
what is sudden cardiac death?
abrupt cessation of effective heart/ cardiac activity
what do thrombolytics do?
they break down blood clots
what is the cardiac muscle biomarker, troponin?
an indicator of heart muscle injury
CAD is the disease of the heart due to decreased blood supply from the narrowing + obstruction from:
atherosclerosis
What are 6 of the modifiable risk factors of CAD?
-DM
-obesity
-smoking
-HTN
-high cholesterol
-physical inactivity
What are some things that put women, specifically, at risk of CAD? (4)
-anemia (during pregnancy)
-early menopause
-Endometriosis
-hormonal birth control
Lipitor is the brand name for AtorvaSTATIN - these drugs are used to lower cholesterol + reduce risk of MI, stroke etc. what are some side effects of -statin drugs?
LIPITOR
-Liver issues
-Increased blood sugar
-Pain in the muscles
-Impaired memory
-Tiredness/ fatigue
-Other (headaches)
-Rhabdomyolysis
What is PTCA and how does it restore blood supply to the heart with an obstructed artery?
Percutaneous Transluminal Coronary Angioplasty - a balloon tipped catheter is inserted into the artery and is inflated several times to reopen the artery
How would you describe Directional Coronary Atherectomy to unblock an artery to promote unblocked blood flow?
this procedure uses a rotating blade that is inserted into the artery, and it shaves down the plaque and removes it