Week 1

Question 1

National medicines policy (NMP)

Answer 1

provide Australians with the best health, social and economical outcomes through a highly supportive medicines policy environment

Question 2

Quality use of medicines

Answer 2

All medicines should be
1. Judiciously
2. Appropriate
3. Safely
4. Efficacy

Question 3

Medicines and poisons act

Answer 3

Regulates medications - S2,3,4 and 8
prohibited S9 and 10

Question 4

PBS vs NonPBS

Answer 4

PBS - provides accessible necessary medication to patient for better health and economical outcomes

nonPBS - private prescription, pharmacy charges more than that of a pbs prescription

Question 5

Roles of TGA

Answer 5

• approve of any drug that creates a therapeutic benefit
  -pre market analayse of any new drugs
• post market analyse
• liscening of Aus manufacture
• verify overseas medications

Question 6

Eligibility requirements for a podiatrist to be able to prescribe medications

Answer 6

1. endorsement from the board
2. authority from the state and territory medicines and poisons legislation

Question 7

PharmD

Answer 7

the effect the drug has on the body

Question 8

PharmK

Answer 8

Movement of the drug in the body
ADME

Question 9

Factors that affect absorption of drugs

Answer 9

aqueous and lipid solubility
concentration
area of absorbing surface
contact time with absorbing surface
route of administration

Question 10

1st pass metabolism

Answer 10

when a drug passes through the liver the bioavailability significantly decreases
- amount of available drug in the blood flow after passing through the liver

Question 11

Enteropherpatic shunting

Answer 11

considerable amount of drugs pass from liver to bile and from bile to small intestine but then travel through hepatic portal back to liver then into the blood flow

Question 12

Bioavailability

Answer 12

Amount of drug available when reaches the systemic circuit

Question 13

Low vs high volume of distribution

Answer 13

Low = stuck in the vacucirculation
High = high lipid solubility and able to pass to many areas of the body

Question 14

pro drugs

Answer 14

in inactive form until metabolised by the body is then in active form

Question 15

Half life

Answer 15

time it takes for the drugs active substance to decrease by half

Question 16

Implications of renal impairment for the steady state

Answer 16

if patient has renal impairment - dosage may need to be changes as excretion will be impacted which can lead to toxitcity