Week 1 Flashcards
Mitosis and meiosis
What is cell division?
The process by which cells make more cells
What are the four main reasons cells divide?
- Growth
- Cell replacement
- Healing
- Reproduction
What type of cells undergo mitosis?
Stem cells
What type of cells undergo meiosis?
Sex cells
Describe the genome of eukaryotic cells
Large and linear
Where is DNA located in eukaryotes?
The nucleus
Describe the genome of prokaryotic cells
Small and circular
Where is DNA located in prokaryotes?
The cytoplasm
What are the two stages of the cell cycle?
- M phase (mitosis or meiosis)
- Interphase
What are the four stages of interphase (in order)?
- G1 phase
- S Phase
- G2 phase
- G0 phase (mitosis only)
What occurs during the G1 phase of interphase?
Growth, cellular metabolism
What occurs during the S phase of interphase?
DNA replication (chromosome duplication)
What occurs during the G2 phase of interphase?
Preparation for mitosis/meiosis
What occurs during the M phase of the cell cycle?
Chromosomal separation and cytokinesis
What is interphase?
The time between successive cell division (G1, S, G2)
What is the state of a cell when it exits the cell cycle?
G0
In what state are cells said to be quiescent?
G0
How many chromosomes are in the human genome?
46 chromosomes (23 pairs)
What are homologous chromosomes?
Pairs of chromosomes of the same type (carrying the same set of genes)
What are centromeres?
The constriction site that holds sister chromatids together
What are sister chromatids?
Two identical copies of a chromosome produced by DNA replication
What does ploidy describe?
The number of complete sets of chromosomes in a cell
What is a haploid cell?
A cell with one complete set of chromosomes
How are haploid cells denoted?
n
What is an example of a haploid cell?
A human sperm or egg cell
What is a diploid cell?
A cell with two complete sets of chromosomes (one from father, one from mother)
How are diploid cells denoted?
2n
What is an example of a diploid cell?
Somatic cells
Why are cells still considered diploid after S phase (even though there are now 4 complete sets of chromosomes)?
- The amount of DNA/chromosomes changes, but the actual type doesn’t
- It is a short and transient phase
In mitosis, the amount of _____ changes, but not the ________ ________.
DNA, ploidy level
What is a polyploid cell?
A cell with four or more complete sets of chromosomes