Week 1 Flashcards

1
Q

The water (H2O) molecule has _____ geometry.

A

Tetrahedral

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2
Q

Repulsion

A

A noncovalent interection

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3
Q

Nucleophile-electrophile

A

Electron rich-poor

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4
Q

One water molecule can make ___ hydrogen bonds.

A

4

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5
Q

Acidemia-Alkalemia (Acidosis-Alkalosis)

A

Blood ph Decrease-Increase

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6
Q

Monosaccharides

A

trioses, tetroses, pentoses, hexoses, heptoses, aldoses, ketoses

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7
Q

Glucose have ___ asymmetric carbons

A

4

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8
Q

Cellobiose

A

The repeating disaccharide unit of cellulose

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9
Q

Dihydroxyacetone

A

The simplest ketose

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10
Q

Glyceraldehyde

A

The simplest aldose

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11
Q

Dextrin

A

A group of low-molecular-weight carbohydrates produced by the hydrolysis of starch and glycogen.

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12
Q

Inulin

A

The storage carbohydrate in some plants (a fructose polymer).

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13
Q

For glucose in solution, more than 99% is in the _____ form.

A

pyranose(a six-membered ring)

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14
Q

Enzymes:
1.Oxidoreductases
2.Transferases
3.Hydrolases
4.Lyases
5.Isomerases
6.Ligases

A

1.Transfer of electrons
2.Group transfer reactions
3.Hydrolisis reactions
4.Cleavage of C-C, C-O, C-N, generating double bonds
5.Geometric or structural changes within a molecule
6.Ligation of two molecules in reactions coupled to the hydrolysis of ATP

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15
Q

Turnover number (kcat)

A

Number of substrate molecules converted to
product

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16
Q

Chaperones

A

Proteins that assist the conformational folding or unfolding of large proteins

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17
Q

General double bounds in fatty acids

A

Δ9*, Δ12, Δ15

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18
Q

The double bonds of ________ fatty acids are almost never conjugated, but separated by a methylene group.

A

polyunsaturated

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19
Q

In nearly all naturally occurring unsaturated fatty acids, the double bonds are in the ____
configuration.

A

cis

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20
Q

_______’s absence from the lungs of premature infants causes respiratory distress syndrome.

A

Dipalmitoyl lecithin (two palmitic (16:0), glycerol, phosphate, choline)

21
Q

Cephalin

A

Phosphatidic acid is esterified to ethanolamine

22
Q

Phosphatidylserine plays a role in ______.

A

apoptosis

23
Q

Cardiolipin is virtually exclusive to the inner ________ membrane.

A

mitochondrial

24
Q

The difference between Urasil and Thymine is that Thymine has a ____ group.

A

methil

25
Q

Purine Bases

A

Adenine
Guanine
Hypoksantine
Xantine

26
Q

What contributes the purine synthesis?

A

Aspartate amino
Glutamine amide
Glycine
Bicorbonate
Folate

27
Q

Specific Purine Inhibators

A

6-mercaptopurine (IMP to GMP)
6-thioguanine
Azathioprine (organ transplantation)
Adenine arabinoside (DNA polymerase)
Azaserin

28
Q

What contributes the pyrimidine synthesis?

A

Aspartate amino
Glutamine amide
Bicarbonate

29
Q

What is Glycine’s R group?

A

H

30
Q

What is Alanine’s R group?

A

CH3

31
Q

What is *Valine’s R group?

A

Isopropyl

32
Q

What is *Leucine’s R group?

A

Isobutyl

33
Q

Which amino acids contain sulfur?

A

Cysteine(polar) and *Methionine(apolar)

34
Q

What is Cystin?

A

It is formed by the union of two Cysteines with a disulfide bond

35
Q

What are hydroxy amino acids?

A

Serine and *Threonine (both polar)

36
Q

What are aromatic amino acids?

A

*Phenylalanine(apolar), Tyrosine(polar) and *Tryptophan(apolar)

37
Q

Phenolic amino acid

A

Tyrosine

38
Q

________ contains indole ring.

A

*Tryptophan(heterocyclic)

39
Q

Basic amino acids (base)

A

*Lysine
**Arginine
**Histidine(heterocyclic)

40
Q

Proline(apolar) is an _________.

A

Imino acid (heterocyclic)

41
Q

Histamin protein incluedes __________ and __________.

A

**arginine, *lysine

42
Q

Collagen contains _________ and _________.

A

glycine, **arginine

43
Q

Acidic Amino acids

A

Aspartic acid (aspartate) and Glutamic acid (glutamate)

44
Q

________ is important for hemoglobin synthesis

A

Glycine

45
Q

________ and ________ are the only pure
ketogenic amino acids.

A

*Lysine, *Leucine

46
Q

Mixed ketogenic and glucogenic amino acids:

A

*Isoleucine, *Phenylalanine, Tyrosine and *Tryptophan

47
Q

Micelle

A

Aggregate of surfactant amphipathic lipid molecules dispersed in a liquid, forming a colloidal suspension.

48
Q

_________ is composed of aspartic acid and phenyl alanine. (Acts as sweetening agent)

A

Aspartame

49
Q

_________ helps in absorption of amino acids, protects against hemolysis of RBC(red blood cells) by breaking hydrogen peroxide which causes cell damage. (anti-aging)

A

GSH (Glutathion) (glutamic acid,cysteine
and glycine)