Week 06 - Anaerobic Glycolysis

Question 1

Anaerobic Glycolysis is completely _______ dependent

Answer 1

Carbohydrate

Question 2

Anaerobic glycolysis uses _______ & ______ as fuel (to produce ATP)

Answer 2

Glucose (blood and cell) & Glycogen (cell only)

Question 3

The product of glycolysis is …

Answer 3

pyruvate

Question 4

Pyruvate can be converted into ______ or used for ____ ______ production

Answer 4

converted into lactate or used for aerobic energy production.

Question 5

when lactate is the product or pyruvate, it is called _____ ______

Answer 5

Anaerobic Glycolysis

Question 6

Where does the process of anaerobic glycolysis occur?

Answer 6

In the cytosol of the cell

Question 7

What is Substrate Level Phosphorylation ?

Answer 7

Production of ATP via anaerobic glycolysis

Question 8

Does anaerobic Glycolysis used O2?

Answer 8

No. Does not require O2

Question 9

Anaerobic glycolysis has _____ power but ____ capacity

Answer 9

HIGH power, LOWER capacity. (80 seconds all out activity)

Question 10

______ ions create fatigue & pain

Answer 10

Hydrogen ion

Question 11

How efficient is anaerobic glycolysis ?

Answer 11

Not very efficient - about 8% of energy in bonds is converted to ATP

Question 12

Name two fates of lactate

Answer 12

1. Leave cell -> blood -> liver -> gluconeogenesis (make glucose)
2. Remain in cell -> pyruvate -> TCA -> Energy converted to glycogen -> glyconeogenesis (make glycogen)

Question 13

Glucose -> pyruvate -> lactate (in cytosol): Name the system

Answer 13

Anaerobic Glycolysis

Question 14

Glucose -> pyruvate -> into mitochondria for oxidation

Answer 14

Aerobic Glycolysis

Question 15

Which reaction is Glucose -> Glucose - 6 -P? Is it reversible and how many ATPs used?

Answer 15

1. Hexokinase. Irreversible. 1 ATP used.

Question 16

Which reaction is glucose - 6 - phosphate fructose - 6 - phosphate?

Answer 16

2. glucose phosphate isomerase

Question 17

Is Glucose phosphate isomerase reversible?

Answer 17

Yes

Question 18

Glucose phosphate isomerase converts _____ into ______

Answer 18

glucose into fructose

Question 19

Which reaction is Fructose - 6 - phosphate -> fructose -1, 6- bisphosphate?

Answer 19

3. Phosphofructokinase (PFK)

Question 20

Is Phosphofructokinase (PFK) reversible?

Answer 20

No

Question 21

_________ controls the overall rate of glycolysis (flux of glycolysis)

Answer 21

Phosphofructokinase (PFK)

Question 22

Which reaction is Fructose –1,6 – bisphosphate ↔ glyceraldehyde–3–phosphate + dihydroxy acetone–phosphate?

Answer 22

4. Aldolase

Question 23

Aldolase converts ____ to _____

Answer 23

6 - Carbon molecule into 2 Carbon molecules.

Question 24

is Aldolase reversible?

Answer 24

Yes

Question 25

Which reaction is Dihydroxyacetone phosphate ↔ glyceraldehyde–3–phosphate ??

Answer 25

5. Triosephosphate isomerase

Question 26

is Triosephosphate isomerase reversible?

Answer 26

Yes

Question 27

Which reaction is Glyceraldehyde–3–phosphate ↔ 1,3 bisphosphoglycerate?

Answer 27

6. Glyceraldehyde phosphate dehydrogenase

Question 28

is Glyceraldehyde phosphate dehydrogenase reversible?

Answer 28

Yes

Question 29

Which reaction is 1,3 bisphosphoglycerate ↔ 3-phosphoglycerate??

Answer 29

7. Phosphoglycerate kinase

Question 30

Is Phosphoglycerate kinase reversible?

Answer 30

Yes

Question 31

Is Phosphoglycerate kinase oxidative phosphorylation?

Answer 31

No. it is Substrate level phosphorylation

Question 32

Which reaction is 3 – phosphoglycerate↔ 2 – phosphoglycerate?

Answer 32

8. Phosphoglycerate mutase

Question 33

Is Phosphoglycerate mutase reversible?

Answer 33

Yes

Question 34

In Phosphoglycerate mutase the Carbon number ____ is moved to Carbon number _____

Answer 34

3 C to 2 C

Question 35

Which reaction is 2 – phosphoglycerate ↔ Phosphenol pyruvate + H2O

Answer 35

9. Enolase

Question 36

Is Enolase reversible?

Answer 36

Yes

Question 37

Enolase removes _____

Answer 37

H2O

Question 38

Which reaction is Phosphoenol pyruvate → Pyruvate

Answer 38

10. Pyruvate Kinase

Question 39

Is Pyruvate Kinase reversible?

Answer 39

No

Question 40

Is Pyruvate Kinase Substrate level phospohrylation? (in cytosol)

Answer 40

Yes

Question 41

Which reaction Pyruvate Lactate

Answer 41

11. Lactate dehydrogenase (LDH)

- Reversible

Question 42

Name 3 fates iof pyruvate

Answer 42

1. Lactate (Cytosol - Anaerobic glycolysis)
2. Pyruvate to TCA cycle (Mitochondria - aerobic)
3. Alanine (AA) - occurs in ex’s