Module 10 - Metabolic and genetics responses to exercise

Question 1

A ligand forms a complex with a ______ to serve a biological purpose

Answer 1

biomolecule (protein)

Question 2

In protein-ligand binding, the ligand produces a signal by …?

Answer 2

Binding to a site on the target protein

Question 3

Binding of ligand usually results in …?

Answer 3

Change of conformational isomerism (3D shape) of the target protein

Question 4

The ligand involved is called the _____

Answer 4

Effector

Question 5

The effector can be classified as either ____ or an _____

Answer 5

activator or an inhibitor

Question 6

_______ is using a substance that is a product further down the line of the reaction pathway, to inhibit the enzyme in the committed step

Answer 6

Feedback inhibition

Question 7

Allosteric Regulation of Enzymes is how fast?

Answer 7

Almost instantaneous

Question 8

Is Allosteric Regulation of Enzymes reversible?

Answer 8

Yes

Question 9

Is Covalent modification faster or slower than Allosteric Regulation ?

Answer 9

Slower (few seconds)

Question 10

The addition of (functional) chemical groups to the enzyme through the formation of covalent bonds

Answer 10

Covalent modification

Question 11

_____ [Substrate] increases reaction rate

Answer 11

increasing

Question 12

_______ [Substrate] decreases reaction rate

Answer 12

Decreasing

Question 13

_________ [Product] decreases reaction rate

Answer 13

Increasing

Question 14

_________ [Product] increases reaction rate

Answer 14

Decreasing

Question 15

__________ [Enzyme] increases reaction rate

Answer 15

Increasing

Question 16

In Glycogenesis, glycogen phosphorylation is activated by… (2)?

Answer 16

phosphorylation & AMP binding

Question 17

In exercise does Ca+ increase or decrease?

Answer 17

Increase

Question 18

Adrenaline increases ___ ____ activity via the cyclic AMP cascade

Answer 18

Glycogen phosphorylase

Question 19

What happens to blood glucose during exercise depends on… (2)

Answer 19

1. Kind of exercise

2. Size of liver glycogen stores

Question 20

What does moderate to high intensity exercise do to blood glucose levels?

Answer 20

Levels increase initially then decrease