WBCs Flashcards
Granulocyte Maturation Series
Myloblast Promylocyte Mylocyte Metamylocyte Specific Granulocyte
Myloblast
High nuclear to cytoplasmic ratio Nucleus is round Cytoplasm is blue No granules In bone marrow
Promylocyte
Granules begin to form
Chromatin starts to clump
In bone marrow
Mylocyte
50/50 cytoplasm to nuclear ration
Cytoplasm turning pink
Specific grnaules
In bone marrow
Metamylocyte
kidney shaped nucleus
in bone marrow
50/50 nucleus to cytoplasm ratio
Band
nucleus 2/3 indented
In circulation
Seg
Segmented nucleus
In circulation
acidic cytoplasm
Mitotic Pool
Myloblast, Promylocyte, Mylocyte
Nonmitotic Pool
Metamylocyte, Band, Seg
Neutrophil Maturation TIme
9 days
Marginal Pool
Lines the walls of the bloods vessels
Circulating Pool
part of the WBC count; good around in the blood
Neutrophils in inflammatory response
Margination, Chemotaxis, Opsonization
Neutrophils Kill bacteria by
Direct Hit
Acidic Environment
Formation of H202 from glucose to lactate
Granule type in Promylocyte
Myloperoxidase