WBCs Flashcards
Granulocyte Maturation Series
Myloblast Promylocyte Mylocyte Metamylocyte Specific Granulocyte
Myloblast
High nuclear to cytoplasmic ratio Nucleus is round Cytoplasm is blue No granules In bone marrow
Promylocyte
Granules begin to form
Chromatin starts to clump
In bone marrow
Mylocyte
50/50 cytoplasm to nuclear ration
Cytoplasm turning pink
Specific grnaules
In bone marrow
Metamylocyte
kidney shaped nucleus
in bone marrow
50/50 nucleus to cytoplasm ratio
Band
nucleus 2/3 indented
In circulation
Seg
Segmented nucleus
In circulation
acidic cytoplasm
Mitotic Pool
Myloblast, Promylocyte, Mylocyte
Nonmitotic Pool
Metamylocyte, Band, Seg
Neutrophil Maturation TIme
9 days
Marginal Pool
Lines the walls of the bloods vessels
Circulating Pool
part of the WBC count; good around in the blood
Neutrophils in inflammatory response
Margination, Chemotaxis, Opsonization
Neutrophils Kill bacteria by
Direct Hit
Acidic Environment
Formation of H202 from glucose to lactate
Granule type in Promylocyte
Myloperoxidase
Granules in Neutrohpils
Alkaline Phosphotase
Granules in Eosinophils
Major Basic Protein
Granules in Basophils
Heparin and Histamine
Eosinophils in tissues
6 days
Eosinophils size
10-15 microns
Basophils in circulation
8-10 hours
Neutrophils in circulation
8-10 hours
Neutrophils in tissues
5 days
Lymphocyte Maturation Series
Lymphoblast
Prolymphocyte
Lymphocyte
Lymph Size
6-18 microns
Types of Lymphs
B and T cells(80%)
Monocyte Size
10-30 microns
Monocyte Circulation
70 hours
Monocyte Morph
nucleus has brain like convolutions; cytoplasm has fine azurophilic granules
VCS technology
Y - light scatter
X - volume
Z - conductivity
Lymphs are bottom left, Monocytes above lymphs
Neutrophils to the right of monos and Eosinophils to the right of Neut