RBCs Flashcards

1
Q

Maturation Series

A
Rurbriblast
Prorubricyte
Rubricyte
Metarubricyte
Reticulocyte or Polychromat
Mature RBC
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2
Q

Rubriblast

A

open chromatin
No hemoglobin synthesis
ALA synthesis

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3
Q

Prorubricyte

A

Begin of Hb synthesis

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4
Q

Rubricyte

A

Peak of Hb synthesis

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5
Q

Metarubricyte

A

All Hb synthesis

Nucleus degenerate mass(pyknotic)

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6
Q

Polychromat

A

Wright Stain

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7
Q

Retic

A

New Methylene Blue

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8
Q

RBC Maturation

A

72 hours to retic which circulates for about 2 days and then mature

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9
Q

RBC Metabolism

A

EM pathway
HM shunt
RL pathway

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10
Q

EM pathway

A

glucose to lactate; 90%; makes ATP

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11
Q

ATP in RBCs

A

Flexibility
Biconcave shape
Sodium-potassium pump
– sodium on outside

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12
Q

Erythropoeitin

A

hormone produce by kidneys to remedy low oxygen

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13
Q

Lipemia

A

lipids on RBCs that cause a falsely high hemoglobin

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14
Q

Reticuloendothelial system

A

site of RBC catabolism; 90% extravascular

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15
Q

Blood Vessel

A

site of 10% of RBC breakdown; broken to a dimer and transported with haptoglobin to the RES

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16
Q

Sites for Bone Marrow Aspiration

A

iliac crest

sternum

17
Q

Active Bone Marrow

A
Spleen
Sternum
Skull
Ribs
Bones
18
Q

ESR

A

the distance cells fall after being mixed with anti-coag and placed in tube

19
Q

Factors Affecting ESR

A

Rouleux or agglutination, increased fibrinogen, temperature