WBCs

Question 1

Neutrophils on Blood Film

Answer 1

have nuclear lobes (2-5)

Question 1

Eosinophils on Blood Film

Answer 1

2 spherical nuclear lobes with orangey granulation

Question 2

Basophils on Blood Film

Question 3

What is the most abundant WBC?

Answer 3

Neutrophils

Question 4

what is the normal amount of lobes for a neutrophil to have and what do deviations to this mean?

Answer 4

2-5
<2 = immature neutrophil (band neutrophil or left-shifted neutrophil)
>5 = hypersegmentation - b12 deficiency

Question 5

where are neutrophils stored? why?

Answer 5

in bone marrow so that they can be rapidly released on bacterial infection

Question 6

What is the function of a neutrophil?

Answer 6

Limit how much microbes can grow after infection which can then be destroyed

Question 7

What is chemotaxis?

Answer 7

movement in response to a chemical stimulant –

Question 8

Explain how a neutrophil achieves its function in 5 steps

Answer 8

Chemotaxis​

Binding to the bacterium​

Engulfment and phagosome formation​

Phagolysome formation​

Degradation of the bacterium

Question 9

What is the function of an eosinophil?​

Question 10

Explain how an eosinophil achieves it’s function​

Question 11

Eosinophils have an Antiparasitic function. What does this mean and how do they achieve this?​

Question 12

What type of blood cell is responsible for the expression of conditions such as asthma and hay fever?​

Question 13

what is the least common WBC?

Answer 13

Basophils

Question 14

What is the function of a basophil?​

Question 15

Explain how a basophil achieves it’s function​

Question 16

Where do monocytes derives from?​

Question 17

Describe what monocytes look like on blood film

Answer 17

indentation to one side of the nucleus​

Question 18

What is the function of a monocyte?​

Answer 18

How does it achieve this function?​

Question 19

what is the second most abundant WBC?

Answer 19

lymphocytes

Question 20

Describe what a lymphocyte is​

Question 21

What is the function of a lymphocyte?​

Question 22

what are the different types of lymphocytes?

Question 23

where do lymphocytes derive from?

Question 24

Lymphocyte levels refer to in terms of diagnosis?

Answer 24

viral infection or leukaemia​

Question 25

How do you tell the difference heamatologically between cT and hT and B cells?​

Question 26

Term for raised Neutrophils

Answer 26

neutrophilia

Question 27

Term for low Neutrophils

Answer 27

neutropenia

Question 28

Term for raised lymphocytes

Answer 28

Lymphocytosis

Question 29

Term for low lymphocytes

Answer 29

Lymphopenia / lymphocytopenia

Question 30

Term for raised monocytes

Answer 30

monocytosis

Question 31

Term for low monocytes

Answer 31

monocytopenia

Question 32

Term for raised eosinophils

Answer 32

eosinophilia

Question 33

Term for low eosinophils

Answer 33

eosinopenia

Question 34

Term for raised basophils

Answer 34

Basophilia

Question 35

Term for low basophils

Answer 35

Basopenia