WBC - Heme 1 Essay Review Flashcards
What do white blood cells begin as?
Undifferentiated stem cell
What is the cell line of the lymphoid system?
Lymphoid stem cell
Lymphoblast
Prolymphocyte
Lymphocyte
What is a lymphoblast?
first differentiated cell in series.
large nucleus
finely reticular
deeply basophilic cytoplasm
What is a prolymphocyte?
between a blast and a cyte
What is a lymphocyte?
round/oval
dense nucleus
robin’s egg blue cytoplasm
What is a B lymphocyte?
Bone marrow
antibody producers
What is a T lymphocyte?
Thymus
antigen recognizers
What is the cell line of a monocyte?
Undifferentiated stem cell myloid stem cell Monoblast Promonocyte Monocyte Macrophage
What is a monocyte?
garbage disposal
large cell w/irregulary shaped nucleus
Gray cytoplasm with ground glass appearance
What are the cells in the myloid series?
Undifferentiated stem cell Myeloblast Promylocyte Mylocyte Metamylocyte Band Seg
What is a myeloblast?
first recognized cell in series
Finely reticular, deeply basophilic cytoplasm
What is a promylocyte
slightly larger than a blast
primary granules
may have nucleoli
basophilic cytoplasm
What is a mylocyte
determining stage of neutro, baso, or eosin
secondary granules
round nucleus
chromatin condensing, flattened on one side
“dawn of neutrophilia”
What is a metamylocyte
smaller than mylocyte
kidney shaped nucleus with dense chromatin
pink cytoplasm no blue background
What is a band?
marked by a U-shape or deeply indented nucleus
Heavily clumped chromatin
What is a seg?
coarsely clumpled chromatin
pink cytoplasm
most common in peripheral blood
What is a neutrophil?
Ingest bacteria, seen in bacterial infections
Rose-violet granules, LAP
What is an eosinophil?
Found in allergies and parasites
Red orange with antihistamine
What is a basophil?
Rare
blue/black with histamine and heparin
What are surface markers
proteins or carbs on the cell surface
What do surface markers identify?
the stage of maturation and lineage of the cell
How can you tell the difference between a B lymph and a T lymph?
surface markers
How are surface markers useful in AIDS?
surface markers determine if an HIV patient is converting to AIDS