H1T3 Review

Question 1

The process whereby blood is ready and able to become a solid in a needed area; and remain flowing as a liquid elsewhere is

Answer 1

hemostasis

Question 2

The function of factor XIII is

Answer 2

stabilize fibrin monomers

Question 3

A patient presents with deep bleeding and possible hemerthroses. There is no evidence of a wound. What is likely responsible?

Answer 3

Primary hemostasis

Question 4

Which factors are involved in activating the intrinsic system and require contact with a negatively charged surface for their activation?

Answer 4

Factors XII, XI, kallikrein, HMWK

Question 5

The average life span of a platelet in the peripheral blood is approximately _____ days.

Answer 5

10

Question 6

The soluble pieces formed during fibrinolysis are called _____.

Answer 6

fibrin split products

Question 7

As part of clot initiation, platelets release _____.

Answer 7

All of these

Question 8

Platelet production is regulated by _____.

Answer 8

Thrombopoietin

Question 9

The average platelet count ranges from _____ of whole blood.

Answer 9

150 - 400 x 10^3/uL

Question 10

A patient is placed on heparin therapy. The dosage is monitored using the following test:

Answer 10

Partial thromboplastin time

Question 11

A patient is placed on Plavix therapy. The dosage is monitored using the following test:

Answer 11

none of these

Question 12

In the extrinsic pathway, what is NOT a part of the activation of factor X

Answer 12

HMWK

Question 13

Which coagulation factor can activate plasminogen?

Answer 13

XII

Question 14

What is factor I?

Answer 14

Fibrinogen

Question 15

What is factor II?

Answer 15

Prothrombin

Question 16

What is factor IV?

Answer 16

Ionic calcium

Question 17

What is factor VIII?

Answer 17

antihemophilic factor

Question 18

What is factor IX?

Answer 18

Christmas factor

Question 19

What is factor XII?

Answer 19

Hageman factor

Question 20

What is factor XIII?

Answer 20

Fibrin stabilizing factor

Question 21

Platelets begin to be separated by _____ within the megakaryocyte.

Answer 21

Demarcation membrane system

Question 22

The “cascade” theories state that most of the activated coagulation factors function as:

Answer 22

enzymes

Question 23

Thrombocytosis is classified as:

Answer 23

Platelet count more than 500 x 10^3/uL

Question 24

A patient presents with purpura and epistaxis. Which of the following tests might be abnormal?

Answer 24

Platelets

Question 25

Following repair of the tissue, when the clot is no longer needed it is removed by

Answer 25

Fibrinolysis

Question 26

Each of the following is involved in hemostasis except

Answer 26

regulation of blood pressure

Question 27

What is it called when platelets bind to the blood vessel surface?

Answer 27

Platelet adhesion

Question 28

Which describes the events involved in secondary hemostasis?

Answer 28

lead to the formation of a chemically stable fibrin clot

Question 29

What is NOT a function of platelets.

Answer 29

Carry nutrients

Question 30

The antihemophilic factor is

Answer 30

VIII

Question 31

What activates the intrinsic pathway?

Answer 31

Exposure to negatively charged surfaces

Question 32

Approximately what portion of the platelets released into the circulating bloodstream are sequestered in the spleen

Answer 32

1/3

Question 33

What bone marrow cell is the precursor of platelets?

Answer 33

Megakaryocyte

Question 34

The process of breaking down a clot is called

Answer 34

Fibrinolysis

Question 35

The proteolytic enzyme that is responsible for fibrinolysis

Answer 35

Plasmin