WBC Flashcards

1
Q

where do WBC come from

A

Haematopoetic stem cells in the bone marrow

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2
Q

where are HSC found

A

boen marrow

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3
Q

granulocytes

A

granulocytes are WBC with granule proteins

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4
Q

agranulocytes

A

WBC without granules

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5
Q

purpose of granules in granulocytes

A

proteolytic enzymes and lysosomes to break down cell walls

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6
Q

granulocyte examples

A

Neutrophils
Eosinophhils
Basophils

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7
Q

where does a macrophage come from,

A

monocyte

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8
Q

neutrophil

A

phagocytosis and chemotaxis

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9
Q

monocyte 3

A

phagocytosis and chemotaxis

antigen presentation

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10
Q

macrophage

A

phagocytosisand chemotaxis

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11
Q

oesinophil

A

kill parasites

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12
Q

BASOPHIL 2

A

immune surveillance
spot, seek and slaughter cancer cells
contains histamines for inflammation

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13
Q

the 5 types of WBC in body

A
no one likes mongols eccentric boobs
Neutrophils
Lymphocytes
Monocytes
EOSINOPHILS
Basophils
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14
Q

chemotaxis mechanism for leukocytes

A
adhesion
margination
diapedesis
migration 
phagocytosis
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15
Q

dia

A

through

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16
Q

esis

A

process

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17
Q

what is chemotaxis

A

when cell moves down chemical concentration gradeint

18
Q

first step of chemotaxis

A

adhesion

19
Q

first step of chemotaxis

A

adhesion and migration

20
Q

what happens after adhesion

A

margination

21
Q

what happens after adhesion and margination

A

rolling

22
Q

what happens after diapedesis

A

migration

23
Q

what happens after migration

A

phagocytosis

24
Q

what is margination and adhesion

A

when WBC moves to endothelium and attaches in response to inflammation

25
Q

what is histmaine

A

inflammatory mediator

26
Q

what are natural killer cells

A

a type of lymphocyte

27
Q

what are natural killer cells

A

a type of lymphocyte which kills cancerous cells

28
Q

what do natural killer cells do

A

kill cancer cells

29
Q

haematopoeisis for lymphoid progenitors

A

1 innate (NK) or adaptive(T or B cell)

30
Q

neoplasm

A

tumour

31
Q

leucocytosis

A

WBC condition (too many)

32
Q

leucopenia

A

WBC too few

33
Q

example of leukocytosis

A

basophyllia or lymphocytosis

34
Q

penia

A

que pena because you don’t have enough

deficient

35
Q

example of leucocytosis

A

basophyllia or lymphocytosis

36
Q

what suffixes can denote leucocytosis

A

Phillip or cytosis

37
Q

phylia

A

too many

38
Q

causes of phyllia/cytosis

A
Nice Pret
Neoplasm
Infection
Corticosteroids
Excercise
Pregnancy
Tissue damage
39
Q

causes of penia

A

Chemo or radio therapy
autoimmune disorders
infection

40
Q

anemia

A

too little Hb in blood

41
Q

what type of WBC is a Nk cell

A

lymphocyte