Plamsa Flashcards

1
Q

2 types of fluid in body

A

intracellular

extracellular

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2
Q

extracellular types of fluid

A

interstitial
transcellular
bloodplasma

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3
Q

interstitial

A

fluid between cells/tissue fluid

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4
Q

transcellular

A

fills up spaces in chambers created by epithelial cells

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5
Q

blood plasma

A

liquid part of blood

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6
Q

stitial

A

location

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7
Q

trans

A

across

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8
Q

intracellular type of fluid

A

cytosol

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9
Q

typical blood testueb centrifugation

in order of increasing mass

A

PLASMA
BUFFY COAT
RBC

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10
Q

buffy coat

A

wbc and !!!PLATELETS!!!

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11
Q

how to separate blood protiens

A

electrophoresis

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12
Q

phoresis

A

migration/travel

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13
Q

what can learn from electropherisis

A

number of a given protein

size of a protein

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14
Q

transcellular fluid example

A

cerebrospinal fluid or vitreous humour

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15
Q

2 main plasma proteins

A

globin and albumin

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16
Q

albumin job

A

maintain lower wp in blood so water does not leave

transport hormone

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17
Q

haem group structure

A

iron surrounded my nitrogenous ring with four ligands, O2orH20 and globin ligand above and below

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18
Q

anode

A

+

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19
Q

cathode

A

-

20
Q

don’t PANIC

A
Positive 
Anode 
Negative 
is 
Cathode
21
Q

clotting mechanism

A

fibrinogen–>fibrin–>clot

22
Q

platelets what do they do

A

specialised blood cells that release chemicals to convert fibrinogen into fibrin

23
Q

is fibrinogen soluble

A

yes soluble because less fibrous than fibrin

24
Q

is fibrin soluble

A

Not soluble because more fibrous than fibrinogen

25
Q

main blood ions +

A

Na+
K+
Mg2+
Ca2+

26
Q

main blood ions -

A

Cl-

27
Q

what does Na+K+ pump do

A

3Na+out

2K+in

28
Q

purpose of Na+K+ pump

A

1 allow nerve cells to be polarised so can depolarise and further transmit action potential.
2 take ions NET out of the cell so make wp higher. Otherwise cells lyse by osmosis

29
Q

what is in plasma

A

dissolved proteins
vitamins
hormones
saccharides and lipids

30
Q

relative components of Buffy coat, RBC AND WBC

A

<1% Buffy coat, 45% RBC, 55% plasma

31
Q

serum

A

plasma - clot factors

32
Q

plasma roles

A

clotting
immune system, transport, regulation of enzyme activity
metabolism
heat buffer

33
Q

isolation of plasma

A

treat with anticoagulant
no clotting
therefore clotting factors are not separated out

34
Q

isolation of serum

A

no anticoagulant
clotting caused by platelets
clotting factors can be separated out

35
Q

clotting factors examples

A

fibrin and fibrinogen

36
Q

how can I remember my anode and cathode?

A

Dont Panic
Positive Anode,
Negative is Cathode

37
Q

what does albumin specifically transport

A

hormones

38
Q

Alpha globulin role

A

regulate rate of enzyme activity by acting as an inhibitor

39
Q

Beta globulin role

A

transports (only betas are lorry drivers)

40
Q

what are Gamma globulins

A

normally, but not always IMMUNOGLOBULINS

41
Q

why is Mg2+ an important electrolyte

A

cofactor for glycolysis

42
Q

what happens to cell if not enough ATP

A

Sodium Potassium pump stops working, so Na+ diffuses back in, lower wp, water enters by osmosis§

43
Q

order of abundance of body fluids

A

intracellular
intercellular
plasma
transcellular

44
Q

plasma uses

A

1 diagnosis

2 treatment

45
Q

plasma therapeutic use

A

PASSIVE IMMUNITY

harvest antibodies from a recovered individual, then give them to the the infected indiviudual