Plamsa Flashcards
2 types of fluid in body
intracellular
extracellular
extracellular types of fluid
interstitial
transcellular
bloodplasma
interstitial
fluid between cells/tissue fluid
transcellular
fills up spaces in chambers created by epithelial cells
blood plasma
liquid part of blood
stitial
location
trans
across
intracellular type of fluid
cytosol
typical blood testueb centrifugation
in order of increasing mass
PLASMA
BUFFY COAT
RBC
buffy coat
wbc and !!!PLATELETS!!!
how to separate blood protiens
electrophoresis
phoresis
migration/travel
what can learn from electropherisis
number of a given protein
size of a protein
transcellular fluid example
cerebrospinal fluid or vitreous humour
2 main plasma proteins
globin and albumin
albumin job
maintain lower wp in blood so water does not leave
transport hormone
haem group structure
iron surrounded my nitrogenous ring with four ligands, O2orH20 and globin ligand above and below
anode
+
cathode
-
don’t PANIC
Positive Anode Negative is Cathode
clotting mechanism
fibrinogen–>fibrin–>clot
platelets what do they do
specialised blood cells that release chemicals to convert fibrinogen into fibrin
is fibrinogen soluble
yes soluble because less fibrous than fibrin
is fibrin soluble
Not soluble because more fibrous than fibrinogen
main blood ions +
Na+
K+
Mg2+
Ca2+
main blood ions -
Cl-
what does Na+K+ pump do
3Na+out
2K+in
purpose of Na+K+ pump
1 allow nerve cells to be polarised so can depolarise and further transmit action potential.
2 take ions NET out of the cell so make wp higher. Otherwise cells lyse by osmosis
what is in plasma
dissolved proteins
vitamins
hormones
saccharides and lipids
relative components of Buffy coat, RBC AND WBC
<1% Buffy coat, 45% RBC, 55% plasma
serum
plasma - clot factors
plasma roles
clotting
immune system, transport, regulation of enzyme activity
metabolism
heat buffer
isolation of plasma
treat with anticoagulant
no clotting
therefore clotting factors are not separated out
isolation of serum
no anticoagulant
clotting caused by platelets
clotting factors can be separated out
clotting factors examples
fibrin and fibrinogen
how can I remember my anode and cathode?
Dont Panic
Positive Anode,
Negative is Cathode
what does albumin specifically transport
hormones
Alpha globulin role
regulate rate of enzyme activity by acting as an inhibitor
Beta globulin role
transports (only betas are lorry drivers)
what are Gamma globulins
normally, but not always IMMUNOGLOBULINS
why is Mg2+ an important electrolyte
cofactor for glycolysis
what happens to cell if not enough ATP
Sodium Potassium pump stops working, so Na+ diffuses back in, lower wp, water enters by osmosis§
order of abundance of body fluids
intracellular
intercellular
plasma
transcellular
plasma uses
1 diagnosis
2 treatment
plasma therapeutic use
PASSIVE IMMUNITY
harvest antibodies from a recovered individual, then give them to the the infected indiviudual