water soluble vitamins Flashcards
thiamin population at risk
alcoholics
coenzyme
- all b vitamins form coenzymes, small organic molecules that combine w inactive enzyemes to form active enzymes
function in energy metabolism
thiamin deficiency
beriberi
wernicke korsakoff
riboflavin coenzyme
FMN and FAD
riboflavin name of def
ariboflavinosis
niacin coenzyme
NAD and NADP
niacin synthesis
body can synthesize from tryptophan (amino acid)
Niacin deficiency
pellagra
pantothenic acid
AcCoA
B6 storage site
stored in muscle tissue
B6 risk of toxicity
irreversible nerve damage
B6 anemia
microcytic hypochromic anemia (less hemoglobin in each RBC and smaller size of each RBC)
biotin synthesis
- can be synthesized by microbes
biotin deficiency
- ezcessive consumption of raw eggs
avidin inactives biotin
choline functions
component of ppl
help carnitine move fatty acids into the cells
precursor for acetylcholine
help export VLDL from the liver
folate dietary sources
legumes, leafy greens, avocados, oranges
folate vs folic acid
1 mcg food folate = 0.6 mcg folic acid taken w food
folate as a coenzyme
DNA synthesis, converts vit B12 to coenzyme form
folate deficiency during preg
spina bifida, anecephaly
neural tube defects
no development of spinal cord (20-28 days post conception)
folate deficiency anemia
megaloblastic, macrocytic anemai
vitamin b12 dietary sources
naturally found in only animal producst
b12 populations at risk of deficiency
stored in liver
vegans
malabsorption
less stomach acid (old ppl)
b12 absorption
- salivary glands produce R-protein
- HCL and pepsin release vit b12 bound to protein in food
- intrinsic factor secreted
- vit b links with IF
- vit b and IF compound absorbed into blood
- excess b12 stored in liver
b12 anemia a deficiency causes
macrocytic anemia
vitamin C sources
citrus, peppers, green veg
vitamin C deficiency
scurvy
vitamin C pop at high risk of def
smokers,
vita C function
antioxidant, collagen
vitamin C and non heme iron
enhances non heme iron absorption
biotin
coenzyme in carboxylase reactions (incorporate CO2 in a substrate)
thiamin coenzyme
TPP (thiamin pyrophosphate)
food sources of thiamin
wide variety of small amt of foods
vitamin b6 functions
PLP coenzyme involved in transamination
synthesis of heme