Walters Practice Questions

Question 1

Is the drug that causes hemorrhagic cystitis a vesicant?

Answer 1

NO

Question 2

What should you take along with the drug that causes metaphase arrest and makes cells accumulate in G-2 and S phase?

Answer 2

ARA-C (drug is Vinblastine)

Question 3

Loss of Achilles Reflex is a side effect of a drug that has what MOA?

Answer 3

Binds tubuline and causes metaphase arrest (drug is Vincristine)

Question 4

Dexrazoxane is the tx for the side effect of which drug?

Answer 4

Doxorubicin (tx is cardiotoxicity)

Question 5

This drug targets B cells and leads to lysis through Ab & complement-dependent cytotoxicity. What class is it a part of?

Answer 5

Monoclonal Antibodies (drug is Almetzumab)

Question 6

What is the major side effect for the drug that metabolizes aldophosphamide to phosphor amide mustard?

Answer 6

Hemorrhagic cystitis (drug is Cyclophosphamide)

Question 7

What are the two most common side effects for the drug that interferes w/topoisomerase II?

Answer 7

Turns urine red and cardiotoxicity (drug is Doxorubicin)

Question 8

Which class of biological response modifiers can produce fatal neuropsychiatric, autoimmune, ischemic and infectious disorders?

Answer 8

Interferons

Question 9

What are the two most significant side effects of the drug that is a recombination of IL-2 and diphtheria toxin?

Answer 9

Hypersensitivity and vascular leak syndrome (drug is Denileukin Diftitox)

Question 10

Who should not be given the drug that inhibits angiogenesis?

Answer 10

Pregnant ladies (Pregnancy Category X) (drug is Thalidomide)

Question 11

What drug class works against Philadelphia Chromosome (9:22)?

Answer 11

BCR-ABL Tyrosine Kinase Inhibitors