w3 - sodium and water balance Flashcards

1
Q

which hormone controls water balance

A

Anti-diuretic hormone

anti-diuretic = anti-pee

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2
Q

ADH causes water to be reabsorbed from the __ ___, high levels produces ___ volume of conc. urine. Concentrated urine indicates __ osmolarity

A

renal tubules
small
high

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3
Q

what controls sodium balance

A

steroids - from adrenals

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4
Q

mineralcorticoid activity is the

A

effect of steroids on Na+

-refers to Na+ reabsorption in renal tubules, in exchange forb K+/H+

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5
Q

what is the main steroid with mineralcoritcoid activiy

A

aldosterone

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6
Q

too much mineralcortcicoid activity means sodium __

A

gain

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7
Q

water can travel anywhere but sodium is confined to the

A

extracellular fluid

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8
Q

t/f sodium follows water by osmsosis

A

false

water follows sodium, so los/gain Na+ = loss/gain water

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9
Q

signs of reduced Sodium

A

reduced sodium = reduced ECF

 incr pulse
postural hypotension
dec urine output 
dec consciousness
dec skin turgor 
dry mouth 
soft-sunken eyes
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10
Q

signs of incr sodium

A
coughing 
tiredness
SOB
pleural effusioin 
ascites 
pulmonary oedema 
reduced heart pumping
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11
Q

how can low conc of Na come about 2.

how can high conc. of Na come about - 2

A

increased loss of NA/ reduced Na intake
reduced water excretion/ incr water intake
= reduced conc of Na

incr Na intake/ reduced Na+ loss
incr h20 loss/ reduced water intake
= incr conc of Na

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12
Q
what to if: 
too little sodium 
too much water
too much sodium 
too little water
A

1) - give sodium
2) - fluid restrict
3) - remove sodium
4) give water

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13
Q

which fluid given - saline or dextrose - travels to ICF compartment

A

dextrose (5%)b

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14
Q

low level of Na

A

<120mmol/L

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15
Q

stimuli for ADH can be either osmotic or non-osmotic, 3 examples of non-osmotic

A

hypovolaemia/hypotension
pain
nausea/vomiting

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16
Q

oedema patients are treated with ___ ___ -> cause loss of sodium and water, breaking the cylce of oedema

A

loop diuretics

(altered balance at capillary, ADH +aldosrerone secreted, but much of retained water ends up in interstitial fluid, making it worse

17
Q

`addisons disease is due to adrenal insufficiency, ooutline how this leads to sodium reduction

A

adrenal insufficient

  • cant make enough steroids
  • reduced mineralocorticocoid activity
  • cant retain enough sodium in the kidneys
  • loses sodium + water from EF
  • reduced ECF -> dehydration, dizziness, hypotension
18
Q

other than sodium, what else is affected by addisons disease

A

ACTH

  • excess pigmentation
  • it is degraded, and exposes MSH