W2 Protein Folding Flashcards
why is an amino acid a residue in a protien
after H2O is removed for peptide bond
what is hair made of
keratin helixes
what does ammonium thioglycolate do
breaks disulphide bonds to open hair cuticle
whats the shape of collagen
triple helix
what is the bonds holding together collagen
electrostatic forces
what is the key AA in collagen
glycine
why is glycine so common in collagen
H r group so much smaller
what is collagen seq
G-X-Y
where do H bonds form for collagen helix
between strands
what is osteogenesis imperfecta
brittle bone disease
how dos fibroblasts repair ECM
mechanical tension
how to increase amount of collagen
more proliferation
which is the post translation modification is for gene activiatiom
acetylatiom
how much hydroxyproline is in collagen
14%
how is pro collagen triple helix stablised
chaperone proteins to the golgi apparatus
what is the intermediate before tropocollagen
procollagen
what happens to precollagen
hydroxylated and glycoslyated