W2 Protein Folding Flashcards

1
Q

why is an amino acid a residue in a protien

A

after H2O is removed for peptide bond

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2
Q

what is hair made of

A

keratin helixes

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3
Q

what does ammonium thioglycolate do

A

breaks disulphide bonds to open hair cuticle

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4
Q

whats the shape of collagen

A

triple helix

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5
Q

what is the bonds holding together collagen

A

electrostatic forces

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6
Q

what is the key AA in collagen

A

glycine

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7
Q

why is glycine so common in collagen

A

H r group so much smaller

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8
Q

what is collagen seq

A

G-X-Y

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9
Q

where do H bonds form for collagen helix

A

between strands

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10
Q

what is osteogenesis imperfecta

A

brittle bone disease

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11
Q

how dos fibroblasts repair ECM

A

mechanical tension

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12
Q

how to increase amount of collagen

A

more proliferation

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13
Q

which is the post translation modification is for gene activiatiom

A

acetylatiom

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14
Q

how much hydroxyproline is in collagen

A

14%

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15
Q

how is pro collagen triple helix stablised

A

chaperone proteins to the golgi apparatus

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16
Q

what is the intermediate before tropocollagen

A

procollagen

17
Q

what happens to precollagen

A

hydroxylated and glycoslyated