W1 : Steady State Concentration

Question 1

Minimum Toxic Concentration (MTC)
&
Clinical Significance

Answer 1

MTC refers to the lowest concentration of a drug in the blood that BEGINS TO PRODUCE toxic effects in the body.

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CS: determining safe dosage limits, ensuring efficacy w/o causing toxicity.

Question 2

Therapeutic Range (TR) & CS

Answer 2

TR refers to the concentration range of a drug in the blood stream where it PRODUCES THE DESIRED EFFECT w/o causing toxicity.

CS- ensures safe & effective drug use. within this range) MEC where the drug reliefs the pain and MTC where there are no rest. distress.

Question 3

Minimum Effective Concentration (MEC
&
CS

Answer 3

MEC refers to the minimum concentration in the bloodstream required to produce therapeutic effect.

CS- MEC is critical in determining the correct dosage of medications.

Question 4

Steady State Concentration (SSC) & CS

Answer 4

• where there is a consistent conc. of drug in blood stream as the rate of the drug administration is equal to the rate of drug elimination.

CS: maintaining tr w/o reaching toxicity.