Vulvar Dermatoses Flashcards

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1
Q

List 2 epidermal vulvar dermatoses

List 2 dermo-epidermal junction vulvar dermatoses

A

Epidermal

  • Vulvar dermatitis
  • Vulvar psoriasis

Dermo-epidermal junction

  • Lichen sclerosus
  • Lichen planus
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2
Q

What are characteristic features of vulvar dermatitis?

What are 2 management strategies?

A
  • Outside > inside
  • Pruritic
  • Erythema
  • Lichenification
  • Possible superinfection with S. aureus, candida, Malassezia
  • Care of vulval skin
    • Avoid irritants
    • Regular barrier emollient
    • Soap substitute (cleanser)
  • Topical steroid of adequate potenency
    • Eumovate BID x 2/52, then daily x 2/52, then stop (clobetasol butyrate - class IV)
    • Consider Fucibet (fucidic acid/betamethasone valerate) or Daktacort (2% miconazole/1%hydrocortisone) based on clinical appearances
  • Consider
    • Protopic 0.1% for maintenance
    • Nizoral washes if seborrheic dermatitis tendency
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3
Q

What is the recommended treatment for genital psoriasis?

A
  • Daktacort (2% miconazole/1%hydrocortisone) BID 2/52, then PRN
  • Protopic 0.1% ointment
  • Care of vulvar skin

Consider systemic/biologic treatment

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4
Q

What is a common early sign of lichen sclerosus?

When are the 2 peaks of presentation for lichen sclerosus?

What is an association that requires monitoring?

A

Tearing of the posterior fourchette with intercourse

  • Prepubertal
  • Peri/post menopausal

Increased incidence of squamous cell carcinoma (SCC) <5%

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5
Q

What is this dermatological diagnosis?

A

Vulvar dermatitis or psoriasis

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6
Q

What is this dermatological diagnosis?

A

Lichen sclerosus

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7
Q

What are clinical features of lichen sclerosus?

A
  • Pruritus
  • Tenderness/soreness
  • Irritation of inner vulval skin
  • White atrophic plaques (labia minora, perineum, perianal)
  • Active disease: purpura, erosions, ulceration
  • Architectural change
    • Resorption of labia minora
    • Burying of clitoral hood
    • Shrinking of introitus
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8
Q

What is the recommended management of lichen sclerosus?

A
  • Care of vulval skin
    • Avoid irritants
    • Regular barrier emollient
    • Soap substitute (cleanser)
  • Topical steroid
    • Dermovate BID x 1/12, daily x 1/12, alternating days x 1/12 (clobetasol propionate - Class I)
      • if flares, go back to beginning
      • Aim for <30g in 6/12 = control
  • Surveillance due to increased risk of SCC
  • Discussion regarding sexual function and childbirth
    • consider physiotherapy
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9
Q

What is this dermatological diagnosis?

A

Vulvar lichen planus

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10
Q

What are clinical features of vulvar lichen planus?

What specialty may you need to consult?

A
  • Reticulate white patches
  • Painful erosions and ulcers
  • Scarring leading to adhesions
    • shiny erythema
  • Erosive vaginitis
  • Extravulvar signs
    • Purple polygonal papules on volar wrist
    • Reticulated buccal mucosa
    • Scarring alopecia (lichen planopilaris)

Gynecology - assess vaginal involvement

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11
Q

What is the recommended management of vulvar lichen planus?

A
  • Care of vulval skin
    • Avoid irritants
    • Regular barrier emollient
    • Soap substitute (cleanser)
  • Topical steroids +/- intralesional steroids
    • Dermovate (clobetasol propionate)
  • Systemic treatment may be warranted
    • Acitretin/MTX/MMF
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12
Q

What is this dermatological diagnosis?

How does it present?

When should you consider biopsy?

What is it associated with?

A

Extramammary Paget Disease

  • Red, scaly plaque
  • Unilateral/asymmetrical
  • Irregular poorly defined margins

If no response to treatment in 6 weeks

Adenocarcinoma of anogenital skin

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13
Q

What is this dermatological diagnosis?

What type of glands are involved?

A

Hidradenitis Suppurativa

Apocrine

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14
Q

What is this dermatological diagnosis?

List 3 clinical features

A

Genital Crohn’s disease

  • Unilateral lymphedema
  • Granulomatous rash
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15
Q

List 5 differentials to erythematous patches to vulvar area

A
  • Atopic dermatitis
  • Irritant contact dermatitis
  • Psoriasis
  • Allergic contact dermatitis
  • Candidiasis
  • Lichen planus
  • Extramammary Paget disease
  • Plasma cell vulvitis (Zoon’s vulvitis)
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16
Q

List 5 differentials to red papules and nodules to vulvar area

A
  • Folliculitis/furuncles
  • Hidradenitis suppurativa
  • genital Crohn’s disease
  • SCC
  • Angiomas (angiokeratomas, hemangiomas)
  • Epidermoid cysts
17
Q

List 5 differentials to white patches and plaques to vulvar area

A
  • Lichen sclerosus
  • Vitiligo
  • Lichen planus
  • Candidiasis
  • Lichen simplex chronicus
  • Vulvar squamous intraepithelial lesions
    • Low grade SIL: condylomata acuminata
    • High grade SIL: HPV related precursor
    • Differentiated: non HPV, associated with lichen sclerosus
18
Q

List 5 differentials to white papules and nodules to vulvar area

A
  • Fordyce spots
  • Epidermoid cysts
  • Molluscum contagiosum
  • LSIL/HISL/dVIN
  • SCC
  • Scars (episiotomy)
  • Milia
19
Q

List 5 differentials to vesicles/bullae to vulvar area

A
  • HSV
  • VZV
  • Bullous impetigo
  • Autoimmune blistering conditions
    • Bullous pemphigoid
    • Pemphigus vulgaris
  • Contact dermatitis (allergic or irritant)
  • Hailey-Hailey disease
  • Fixed drug eruption
  • Lymphatic malformation
  • Bullous lichen sclerosus
  • Linear IgA
  • Epidermolyisis bullosa aquisita
20
Q

List 5 differentials to scarring ulcers to vulvar area

A
  • Acute vulvar aphthous ulcers (Lipshütz ulcer)
    • 30% associated with underlying infection (EBV)
    • acute, painful, self-limiting
  • Infection
    • HSV
    • Primary syphilis
  • Trauma
  • Malignancy (SCC, melanoma)
  • Cutaneous Crohn’s disease
  • Pyoderma gangrenosum
21
Q

List 5 differentials to pigmented lesions to vulvar area

A
  • Physiologic hyperpigmentation
  • Postinflammatory hyperpigmentation
  • SIL
  • Melanocytic nevi
  • Angiokeratoma
  • Vulvar melanosis
  • Lichen planus
  • Vulvar melanoma