vomiting, diarrhea, pancreatitis Flashcards
Describe dietary lipid absorption for LCFA
a. Hydrolyzed to monoglycerides (MG) and free FA (FFA) via lipase (of pancreas)
b. Packaged into micelles or lipid droplets (MG + FFA + bile salts)
c. Micelles diffuse across SI into enterocyte
d. Reformed triglycerides in chylomicrons
e. Chylomicrons transported via lymphatics (so lymph system must be working for lipid metabolism to occur), go form lymphatics into blood
Describe dietary lipid absorption for MCFA
a. More water soluble
b. High percentage of dietary MCT absorbed directly into portal bloodstream.
i. Useful source of energy if fat absorption is impaired
c. Prepared by hydrolysis and fractionation of coconut oil
d. One tablespoon (15 ml) = 115 kcal
e. Dose: maximum of 25-30% of calories
Define malassimilation
Failure of nutrients to pass across the intestinal wall in quantities sufficient to maintain
body weight and condition
- includes malabsorption and maldigestion
Malabsorption
diseases that alter structure/function of mucosa plus lymphatics
Maldigestion
Defects in intraluminal digestion as a result of gastric (enzyme), pancreatic (enzymes), or biliary dysfunction
Impaired colonic water/electrolyte absorption, accelerated colonic transport, and loss of bile salts lead to….
diarrhea, specifically steatorrhea (can see greasy, lipid droplets on/in feces
Gut peptide release inhibition of gastric emptying/small bowel transit leads to…
vomiting
Loss of food energy leads to…
weight loss
Loss of EFA (essential fatty acids) leads to…
EFA deficiency; can see dull hair coat
Loss of fat soluble vitamins leads to…
vitamin deficiency; if it is vitamin D will see bone loss
Loss of minerals Ca and Mg leads to…
bone loss
Dietary management of steatorrhea
treat underlying malassimilation (PEI, inflammatory intestinal disorders, motility disorders, short bowel disease)
Dietary management of fat soluble vitamin/EFA deficiencies
- treat underlying malassimilation
- correct dietary levels
- parenteral administration of vitamins
Dietary management of weight loss
ensure adequate kcal intake
Dietary management of bone loss
treat underlying malassimilation