Vol. 5 Flashcards
Clozapine seizure effect
lowers threshold
G6PD triggers
infections and drugs (sulfa, antimalarials, nitrofurantoin)
Most common metastatic brain cancers
lung > breast > unknown primary > melanoma > colon
tx severe hyperCa
> 14 mg/dL, NS and calcitonin. Avoid loops unless volume overloaded
erysipelas cause
GABHS (strep pyo), raised borders
cocaine and fetal effects
jejunal atresia (triple bubble: stomach, duodenum, jejunum)
Theophylline tox
CNS stim. and cardiac tox
PPV
Of all patients with positive test, what fraction is a true positive
best test for recurrent MI
CK-MB
how often nonstress test
weekly in 3rd trimester
pneumocystis tx
bactrim is first line + steroids if severe disease
second line tx for pneumocystis
pentamidine, atovaquone, bactrim and dapsone, clinda and primaquine
Fanconi’s anemia
Pancytopenia and congenital abnormalities
Diamond-Blackfan anemia
Congenital Pure red cell aplasia
endometritis tx
IV clinda and IV aminoglycoside
causes of variable decels
Cord compression, oligohydramnios, cord prolapse
are variable decels always bad
if no relation to contractions, they are common and fine
neuroblastoma origin
neural crest derived
neuroblastoma dx
serum and urine catecholamines (HVA and VMA) elevations, but no pheo sxs
Wilm’s tumor source
Metanephros, renal parenchyma
Herpangina cause
Coxsackie A (B is myocarditis)
dihydropyridine CCBs
nifedipine and amlodipine
non-dihydropyridine CCBs
diltiazem and verapamil
which CCB class causes angioedema
I think the dihydropyridine group???
Pinealoma
commonly GCT, can produce hCG, can cause obstructive hydrocephalus
HSP kidney histo
IgA deposition in mesangium
HSP sxs
palpable purpura, abdominal pain, arthralgias, kidney failure
How does congenital hypothyroidism look
Normal birth, then develops large tongue, abd. bloating, umbilical hernia, weakness, hypotonia, jaundice
Primary amenorrhea definition
No menarche by Age 15
dx for Turners
Karyotype, then FISH
breastfeeding failure jaundice
not enough fluids b/c of not enough breastfeeding means they reabsorb more bile acids . Happens in first week of life
breast milk jaundice
nl breastfeeding, not dehydrated, but high levels of beta-glucuronidase in breast milk lead to more reasbroption. Starts age 3-5 days, peaks at 2 weeks
sodium loss in HHNK
free water loss is great than sodium loss
hemochromatosis infection risk
increased risk to yersinia, vibrio vulnificus, yersinia enterocolitica
Staph aureus PNA
nodular infiltrate with cavitation
can you have MDD episodes in dysthymia?
yes, it just wont be pure dysthymia
janeway lesions
palms and soles, non-painful, macular
osler nodes
painful, violaceous nodules on fingertips and toes
roth spots
edematous and hemorrhagic lesions of the retina (IE)
reye syndrome histo
microvesicular fatty infiltration and hepatic mitochondrial dysfunction
reye syndrome associations
influenza B, then A, and varicella zoster
Macrovesicular fatty chances
alcoholic and NAFLD
what elevated in folate deficiency
homocysteine
what elevated in B12 deficiency
homocysteine and methylmalonic acid
painless hematochezia in a young toddler
Meckel’s diverticulum
antiphospholipid syndrome tx in pregnancy
aspirin and LMWH
indications for parapneumonic tube thoracostomy
pH
tx variant angina
CCBs and nitrates
cat bite tx
amox-clav for pasturella multocida
echinococcus animals
sheep and dogs
klumpke paralysis hand
CLAW
Wernicke encephalopathy sxs
encephalopathy, ocular dysfunction, and gait ataxia
Marfan’s lens subluxation
Upwards
MGUS follow up test
metastatic skeletal bone survery
aspirin exacerbated respiratory disease
seen with asthma, chronic rhinosinusitis with nasal polyposis
Tx for baby born to mom with HBV
HBIG and HBV vaccine
tx for antiphospholipid syndrome in pregnancy
low-dose aspirin
thyroid labs
TSH and T4
Tay-Sachs cells apperance
onion-skin lysosomes
Patau apperance
cleft lip/Palate, holoProsencephaly, Polydactyly,
rocker-bottom feet, MR; death by 1 y/o
Patau mnemonic
Puberty is 13
Edwards mnemonic
Election age is 18
Williams syndrome apperance
Elfin facies, Extreme friendliness w/ strangers,
well-developed English, MR
Williams mutation
7q-
Cri-du-chat mutation
5p-
Cri-du-chat appearance
microcephaly, cardiac problems, high-pitched
meowing, epicanthal folds, MR
Eisenmenger syndrome
Pulmonary HTN reversing direction of shunt
ASD presentation
low-grade systolic murmur, fixed S2, and frequent colds
When to get prenatal imaging
Level-I U/S at 18-22 wks is standard of care
Wilson disease dx
Low serum ceruloplasmin, increased urinary copper, kaiser-fleischer rings