Vocab for Body Systems Flashcards
Drugs
Medicines/Substances used to prevent or treat a condition or disease
L.A.D.M.E.
Liberation
Absorption
Distribution
Metabolism
Excretion
Addiction
Physical & Psychological dependence on and craving for a drug
Additive Action
Drug action in which the combination of two similar drugs is equal to the sum of the effects of each
Aerosol
Particles of drug suspended in air
Anaphylaxis
Exaggerated hypersensitivity reaction to a previously encountered drug or foreign protein
Antagonistic Action
Combination of two drugs give less than an additive effect
Antidote
Agent given to counteract an unwanted effect of a drug
Brand Name
Commercial name for a drug
Trademark or Trade name
Chemical Name
Chemical formula for a drug
Generic Name
Legal noncommercial name for a drug
Contraindications
Factors that prevent the use of a drug or treatment
Controlled Substances
Drugs that produce tolerance and dependence that have potential for abuse or addiction
Dependence
Prolonged use of a drug that may lead to a physiologic need for its actions in the body
Dose
Amount of drug administered
FDA
Food & Drug Administration
US Government agency with legal responsibility to enforce proper drug manufacture and clinical use
Iatrogenic
Condition caused by treatment given by physicians or medical personnel
Idiosyncratic Reaction
Unexpected effect produced in a particularly sensitive patient, but not seen in most people
Medicinal Chemistry
Study of new drug synthesis
Relationship between chemical structure & biological effects
Molecular Pharmacology
Study of interaction of drugs and their target molecules
Oral Administration
Drugs are given by mouth
Sublingual Administration
Drugs are given by placement under the tongue
SL
Rectal Administration
Drugs are inserted through the anus into the rectum
Inhalation
Administration of drugs in gaseous or vapor form through the nose or mouth
Topical Application
Drugs are applied locally on the skin or mucous membranes of the body
Parenteral Administration
Drugs are given by injection into the skin, muscles or veins
Intracavitary; Intradermal; Intramuscular (IM); Intrathecal; Intravenous (IV); Subcutaneous (SC) or (SQ) or (subQ)
Pharmacist
Pharmacology Professional - PharmD
Specialist in preparing and dispensing drugs
Pharmacy
Location for preparing and dispensing drugs
The study of preparing and dispensing drugs
Pharmacologist
Pharmacology Professional - MD or PhD
Specialist in the study of properties, uses, and side effects of drugs
Pharmacodynamics
Study of a drug’s effects in the body
Pharmacokinetics
Study of a drug’s absorption, distribution into body compartments, metabolism, and excretion over a period of time
Pharmacology
Study of the preparation, properties, uses, and side effects of drugs
PDR
Physician’s Desk Reference
Reference book that lists drug products
Receptor
Target substance with which a drug interacts in the body
Resistance
Lack of beneficial response
Response
Desired and beneficial effect of a drug
Schedule
Exact timing and frequency of drug administration
Side Effect
Adverse reaction, usually minor that routinely results from use of a drug
Synergism
Combination of two drugs causes an effect that is greater than the sum of the individual effects of each drug alone
Syringe
Instrument for introducing or withdrawing fluids from the body
Tolerance
Larger and larger drug doses must be given to achieve the desired effect
Toxicity
Harmful effects of a drug
Toxicology
Study of harmful chemicals and their effects on the body
Transport
Movement of a drug across a cell membrane into body cells
USP
United States Pharmacopeia
Authoritative list of drugs, formulas, and preparations that sets a standard for drug manufacturing and dispensing
Vitamin
Substance found in foods and essential in small quantities for growth and good health
A.C. or AC
Before meals
ACE
Angiotensin-converting enzyme
Ad-lib
Freely; As desired
APAP
Acetaminophen
ARB
Angiotensin II Receptor Blocker
B.I.D. or BID
Two times a day
C-
With
Caps
Capsules
CC
Cubic Centimeter
GM or G
Gram
GTT
Drops
H
Hour
H.S. or HS
At bedtime
H2 Blocker
Histamine h2 receptor antagonist
HRT
Hormone Replacement Therapy
INH
Isoniazid-antituberculosis agent
MAOI
Monoamine oxidase inhibitor
MG
Milligram
ML
Milliliter
NPO
Nothing by mouth
NSAID
Non-steroidal anti-inflammatory drug
P-
After
P.C. or PC
After Meals
PCA
Patient controlled analgesia
P.O. or PO
By Mouth
P.R.N. or PRN
As needed; as necessary
PT
Patient
Q
Every
Q.H. or QH
Every hour
Q2H
Every 2 hours
Q.I.D. or QID
Four times a day
Q.S. or QS
Sufficient quantity
QAM
Every morning
QPM
Every evening
RX
Prescription
S-
Without
SERM
Selective estrogen receptor modulator
SIG.
Directions - how to take medication
S.O.S.
If it is necessary
SSRI
Selective serotonin reuptake inhibitor
TAB
Tablet
TCA
Tricyclic antidepressant
T.I.D. or TID
Three times daily
Angiotensin Converting Enzyme (ACE) Inhibitor
Lowers blood pressure by dilating blood vessels.
Block the conversion of angiotensin I to angiotensin II (a powerful vasoconstrictor).
Amphetamine
Caffeine
Central nervous system stimulant
Analgesic
Relieves pain
Androgen
Male hormone
Anesthetic
Reduces or eliminates sensation; general and local
Angiotensin II Receptor Blocker
Lowers blood pressure by preventing angiotensin from acting on receptors in blood vessels
Antacid
Neutralizes acid in the stomach
Antiandrogen
Blocks formation of androgens or interferes with their effect in tissues
antiarrhythmic
Treats abnormal heart rhythms
Antibiotic
Chemical substance, produced by a plant or microorganism, that has the ability to inhibit or destroy foreign organisms in the body
Anticoagulant
Prevents blood clotting
Anticonvulsant
Prevents convulsions (abnormal brain activity)
Antidepressant
Relieves symptoms of depression
Antidiabetic
Given to prevent or treat diabetes mellitus
Antidiarrheal
Prevents diarrhea
Antiemetic
Antinauseant
Prevents or relieves nausea and vomiting
Antihistamine
Blocks the action of histamine and helps prevent symptoms of allergy
Antimicrobial
Agent that kills microorganisms or stops their growth
Antiplatelet
Reduces the tendency of platelets to stick together and form a clot
Antiulcer
Inhibits the secretion of acid by cells lining the stomach
Antiviral
Acts against viruses such as herpes viruses and HIV
Aromatase Inhibitor
Reduces estrogen in the blood by blocking the enzyme aromatase
Beta Blocker
Beta-Blocker
Blocks the action of epinephrine at sites on receptors of heart muscle cells, the muscle lining of blood vessels, and bronchial tubes; antiarrhythmic, antianginal, and antihypertensive.
Bisphosphonate
Prevents bone loss in osteoporosis
Calcium Channel Blocker
Calcium Antagonist
Blocks the entrance of calcium into the heart muscle and muscle lining of blood vessels; used as an antiarrhythmic, antianginal, and antihypertensive;
Cardiac Glycoside
Drug that treats heart failure by increasing the force of contraction of the heart
-Digoxin is an example
Cardiovascular Drug
Acts on the heart and blood vessels.
Includes ACE Inhibitors, Beta Blockers, Calcium Channel Blockers, Statins, and Diuretics
Cathartic
Relieves constipation
Cholesterol-Binding Drug
Binds to dietary cholesterol and prevents its uptake from the gastrointestinal tract
Cholesterol-Lowering Drug
Statin
Lowers cholesterol by preventing its production by the liver
Diuretic
Antihypertensive
Increases the production of urine and thus reduces the volume of fluid in the body
Emetic
Promotes vomiting
Endocrine Drug
Hormone or Hormone-like drug
- Androgens, Estrogens, Progestins, SERMS, Thyroid Hormones & Glucocorticoids
Estrogen
Female Hormone that promotes development of secondary sex characteristics and supports reproductive tissues
Gastrointestinal Drug
Relieves symptoms of diseases in the gastrointestinal tract
- Antacids, Antiulcers, Antidiarrheals, Cathartics, Laxatives, Purgatives, and antiemetics.
Glucocorticoid
Hormone from the adrenal cortex that raises blood sugar and reduces inflammation
Hypnotic
Produces sleep or a trance-like state
Laxative
Weak cathartic
Narcotic
Habit-forming drug (potent analgesic) that relieves pain by producing stupor or insensibility
- Morphine and Opium
Progestin
Female hormone that stimulates the uterine lining during pregnancy and is also used in treatment of abnormal uterine bleeding and for hormonal replacement therapy.
Purgative
Relieves constipation
Strong cathartic
Respiratory Drug
Treats asthma, emphysema, and infections of respiratory system
Bronchodilators
Sedative
Mildly hypnotic drug that relaxes without necessarily producing sleep
Benzodiazepines
Stimulant
Excites and promotes activity
Caffeine and amphetamines
Thyroid Hormone
Stimulates cellular metabolism
Tranquilizer
Controls anxiety and severe disturbances of behavior
Integumentary System
The skin and its accessory structures (hair, nails, & glands)
Integument means covering
Epidermis
Thin, Cellular Membrane Layer
Contains Keratin
Lacks blood vessels, lymphatic vessels, & connective tissue (elastic fibers, cartilage, fat)
Made of multilayered cells that die at the same rate they are replaced
Within 3-4 weeks after beginning as a basal cell in the deepest part, keratinized cells are sloughed off from the surface of the skin.
Constantly renewing itself, process slows with age
Squamous Epithelium
Stratified Squamous Epithelium
Cells that make up the epidermis, they are flat and scale-like
Cells are arranged in several layers to form this
Basal Layer
Deepest region of the epidermis
Cells are constantly growing and multiplying
As cells divide, they are pushed upward and away from the blood supply by a steady stream of younger cells.
Stratum Corneum
Most superficial layer of the epidermis
Cells flatten, shrink, lose nuclei, die and become filled with keratin.
Keratin
Hard protein material found in epidermis, hair, and nails
Means horn and is commonly found in the horns of animals
Keratinocytes
Cells that are composed of keratin
Come from the stratum corneum
Melanocytes
Special cells in the basal layer that contain the pigment that is transferred to other cells and give color to the skin.
Number in all human races is the same
Melanin
Pigment that gives color to skin
Amount within each cell accounts for the color differences among the races
Eu is black-brown pigment
Pheo is red-yellow pigment
Albinism
Condition wherein melanin is not formed in the skin leaving hair and skin white
Eye color varies and ranges from red to blue to brown depending on the amount of melanin present in the iris.
Occulocutaneous Albinism
Affects eyes, skin, and hair
Ocular Albinism
Affects the eyes only
Dermis
Dense, Fibrous, Connective Tissue layer
Composed of interwoven elastin and collagen fibers.
Elastin
Protein that is elastic and helps skin to return to its original position when pinched or poked
During pregnancy, overstretching of the skin may break the fibers resulting in striae.
Collagen
Fibrous protein material found in bone, cartilage, tendons, ligaments and the skin.
Tough and resistant but also flexible.
In infancy, loose and delicate, becomes harder as the body ages.
Support and protect the blood and nerve networks that pass through dermis.
Diseases affect connective tissues of the body - ex: scleroderma
Striae
Stretch Marks
Subcutaneous Layer
SubQ
Thick, Fat-Containing Tissue
Specializes in the formation of fat
Adipocytes are predominant
Important in protection of the deeper tissues of the body, as a heat insulator and for energy storage
Adipocytes
Fat Cells
Manufacture and store large quantities of fat
Disposition varies in different areas of the body and among individual people
Hair Follicles
Sacs within which each hair fiber grows
Lunula
Semilunar whitish region at the base of the nail plate
Cuticle
Narrow band of epidermis at the base and sides of the nail plate
Paronychium
Soft tissue surrounding the nail border
Onycholysis
Loosening of the nail plate with separation from the nail bed
Sebaceous Gland
Located in the dermal layer of the skin over entire body with exception of palms, soles, lips.
Secrete oily substance
Ducts open into hair follicles through which sebum is released
Influenced by sex hormones, which can cause them to hypertrophy at puberty and atrophy in old age.
Sebum
Oily substance secreted by the sebaceous glands
Contain lipids
Lubricate the skin and minimize water loss
Increased production during puberty contributes to blackhead formation and acne
Sweat Glands
Tiny, coiled glands found on almost all body surfaces
Most numerous in the palm and sole
Originate deep in the dermis and straighten out to extend up through the epidermis
Eccrine Sweat Glands
Most numerous sweat-producing exocrine gland in the skin
Pore
Tiny opening on the surface of the skin at the end of a sweat gland
Sweat
Perspiration
Almost pure water, with dissolved materials such as salt making up less than 1% of the total composition
Colorless and odorless - odor comes when sweat accumulates on the skin and is caused by the action of bacteria on the sweat
Cools the body as it evaporates
Controlled by the sympathetic nervous system
Apocrine Sweat Glands
Large dermal exocrine glands located in the axilla and genital areas
Secretes sweat that in action with bacteria is responsible for human body odor
Lesion
Area of abnormal tissue anywhere on or in the body.
May be caused by disease or trauma
Crust Lesion
Collection of dried serum and cellular debris
- Scab: forms from the drying of a body exudate
Cyst Lesion
Thick-Walled, closed sac or pouch containing fluid(s) or semisolid material(s)
- Pilonidal: found over the sacral area of back in midline and contains hairs
- Epidermoid: collection of yellowish, cheesy sebum commonly found on the scalp, vulva, and scrotum
Erosion Lesion
Wearing away or loss of epidermis
Do not penetrate below the dermo-epidermal junction
Occur as a result of inflammation or injury and heal without scarring
Fissure Lesion
Groove or crack-like sore
- Anal: break in the skin lining of the anal canal
Macule Lesion
Flat, pigmented measuring less than 1 cm in diameter
Freckles, tattoo marks, flat moles
- Patch: large macule, greater than 1 cm in diameter
Nodule Lesion
Solid, round or oval elevated measuring 1 cm or more in diameter
Enlarged lymph node and solid growths