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Biochem Finals Fatima > Vitamins Fat Solube With Vit. C > Flashcards

Vitamins Fat Solube With Vit. C Flashcards

0
Q

Pathway that is converts glucose to vitamin C

A

Uronic acid pathway or glucoronic acid pathway

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1
Q

Among all vitamins this is the one that most easily to destroy

A

Vitamin C

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2
Q

We human do not have enzyme that converts glunolactone to ketoglunolactone, and what enzyme is that?

A

Glunolactone oxylase

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3
Q

Majority of vitamin C is converted to?

A

Oxylic acid

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4
Q

So kung madami ang intake mo ng ascorbic acid. ,arami din yung oxalic acid mo na mastore in your urine. And can precipitate to form your?

A

Oxalate stones

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5
Q

However you can prevent oxalate stone formation if you

A

Drink plenty of water

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6
Q

Among the function of vitamin C the most important is

A

Role in collagen synthesis

Para ma produce si hydroxyproline at hydroxylysine kasi ang dalawang ito kasama si proline ang nagpapatibay sa collagen. Kung walng vit c. Weak yung colagen, eh diba ang collagen halos na sa lahat ng parts ng katwan natin.

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7
Q

Gives tensile strength of collagen

A

Hydroxproline+ hydroxylysine + proline

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8
Q

Vitamin C. Is important in relation in absorption of iron. Conversion of

A

Iron in ferric form Fe3 to ferrous Fe2 para ma absorb ng katwan

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9
Q

Manifestation of early Iron deficiency anemia

A

Slugish and sleepiness

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10
Q

You also need vitamin C to convert ______ to active form

A

Folic acid, kasi pwede kng magkaroon ng macrosytic anemia.

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11
Q

Only way you can excrete your cholesterol is to

A

Convert it to cholic acid or bile acid using vitamin C

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12
Q

Vitamin C is one of the anti cancer vitamins, why?

A

It prevents formation of nitrousamine na nakukuha sa mga food colorant o preservatives

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13
Q

Another function of vitamin C is to potentiate your

A

Immune system

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14
Q

Poor wound healing

A

Scurvy

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15
Q

This junction is only swollen when you have vitamin C deficiency

A

Scorbutic rosary

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16
Q

For vitamin D deficiency, what junction is affected?

A

Rakitic rosary

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17
Q

This actually the one that called anti infective or anti cancer vitamin

A

Vitamin A

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18
Q

The precursor of vitamin is?

A

Carotene

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19
Q

The best carotene is?

A

Beta carotene, because from 1 beta carotene you can get 2 moles of vitamin A

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20
Q

Different types of Vitamin A

A

Retinol
Retinal
Retinoic acid
Dihydroretinol

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21
Q

Least toxic because it is also the least stored among types of vitamin A

A

Retinoic acid

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22
Q

The conversion of carotene to vitamin A takes place primarily in the

A

Liver

And small conversion in intestinal cells

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23
Q

For you to convert carotene to vitamin A you need to have

A

Thyroid hormone
Zinc
Vitamin E
Insulin

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24
Q

Protect vitamin A for being destroyed

25
Q

Needed to transport vitamin E

A

Thyroid hormone
Zinc
Insulin

26
Q

Conversion of beta carotene to vitamin A

A

Beta carotene to
Vitamin A alcohol or retinol to
Vitamin A aldehyde or retinal to
Vitamin A or retinoic acid

27
Q

First rash of the babies

A

Raseola infantum

28
Q

Physiologic function of vitamin A

Role in vision, production of

29
Q

Formula for rhodopsin

A 
Opsin
Vitamin A (11 cis retinal)
30
Q

If no production of rhodopsin, it will lead to

A

Night blinded ness
Nyctopia
Nocturnal blindness

31
Q

Earliest sign of vitamin A deficiency

A

Inability to distinguish green color

32
Q

Another function of vitamin A is

Maintenance of the integrity of epithelial tissues

A

Kaya tinatwag tong anti cancer and anti infection.

About sa dahon na tuyo at bagong usbong, lam mo na yun. Haha

33
Q

Vitamin A function on

Skin

A

Dryness and roughness of the skin, toad skin if deficient sa Vitamin A

34
Q

Vitamin A function on

Role in reproduction

A

If deficient

Atrophy of germinal epithelium
Ni spermatogenesis

35
Q

Vitamin A manifestation

Eye manifestation early symptoms

A

Night blinded ness

Photophobia

36
Q

Drying of the conjunctiva

Bitots spot

A

Xerosis conjunctivae

37
Q

Can be reversed by giving high dose of vitamin A

A

Bitots spot

38
Q

Drying of cornea
Collection of pus and blood
Cornea become soft and jelly like mass

A

Xerosis cornea

39
Q

Softened cornea because of ulceration
Cornea ruptures
Blindness occur

A

Keratomalasia

40
Q

Tandaan mo to drying effects ang epekto kapag low protein diet ka. Kasi hindi ma transport si vitamin A sa mga organs

41
Q

Vitamin D also called

A

Anti rachitiic vitamin

Sunshine vitamin

42
Q

Sources of vitamin D

A

From cholesterol

It requires sunlight

43
Q

Vitamin D metabolism

A 
Cholesterol
UV light
Cholecalciferol
Liver
Hydroxyl reaction
25 dihydroxycholecalciferol
Kidney
Hydroxylation
1,25 dihydroxycholecalciferol
Target tissues
44
Q

Most important function of vitamin D

A

Absorption of calcium and phosphorus

45
Q

Principal function is to maintain the plasma calcium concentration

A

Calcitriol

46
Q

Infection caused by clostridium tetanii

47
Q

State of the muscle, decreased calcium level

48
Q

Function of calcitriol

A

Insulin secretion

49
Q

Vitamin D deficiency

Adults
Lead to tetany
Softening and weakening of the bones

A

Osteomalacia

50
Q

Caput quadratum

Harrison

51
Q

Vitamin E also called

A

Rejuvinating vitamin

52
Q

Vitamin E only true for animals

A

Anti aging

Antisterility

53
Q

Precursors of vitamin E are

A

Tocoperols

Best precursor is alpha tocoperols

54
Q

The requirement of vitamin E is directly proportional to

A

Your fat intake specifically polyunsaturated fatty acid

55
Q

Vitamin e sources

A

Green plants

Wjeat germ oil - highest concentration

56
Q

Physiologic effects of vitamin E

A

Antioxidant property
Maintenance of the integrity of RZbC membrane
Maintains integrity of muscles
Prevents liver necrosis

57
Q

Vitamin K also called

A

Coagulation vitamin

Antihemorrhagin vitamin

58
Q

Vitamin D forms

A

Phylloquinone ( vitamin K1)

Farnoquinone ( vitamin K2)

59
Q

Major form of vitamin K found in plants

A

Vitamin K1

Phylloquinone

60
Q

Function of vitamin K

A

Clotting factors 1972
Component of ETC ( coenzyme Q )
Synthesis of bone calcium binding protein ( osteoclacin )
Synthesis of bone matrix Gla Protein

61
Q

Vitamin Ak inhibitors

A

Dicuormarol

Biochem Finals Fatima (6 decks)

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