Vitamin K Flashcards
Vitamin K is essential for an enzyme. Name that enzyme.
γ-Glutamyl carboxylase
The name of Vitamin K obtained from the plant.
Phylloquinone or Vitamin K1
The name of Vitamin K obtained from intestinal bacteria.
Menaquinone or Vitamin K2
The synthetic form of Vitamin K
Menadione
Vitamin K food sources
Liver Egg yolk Cabbage Spinach Kale
Causes of Vitamin K deficiency
Poor diet Gastrointestinal disorders Neonate whose intestinal flora hasn't been established Failure of liver to produce bile Antibiotics
Vitamin K toxicity symptoms
Hemolytic Anemia
Jaundice
Enzyme Vitamin K epoxide reductase c1 reduces the vitamin k back to hydroquinone to continue the reaction. This enzyme is inhibited by which drug?
Warfarin
The principal role of vitamin K is in the posttranslational modification of a number of proteins most of which are involved in ___________ (transportation/clotting)
clotting
By using antibiotics like cefamandole, the bacterial population is affected causing vitamin k deficiency leading to _____________ (hypoprothrominemia/anemia)
hypoprthrombinemia
It is recommended that all newborns receive an intramuscular dose of vitamin k as prophylaxis to prevent __________________ because newborns lack intestinal flora.
hemorrhagic disease of the newborn