Vitamin K Flashcards

1
Q

Vitamin K is essential for an enzyme. Name that enzyme.

A

γ-Glutamyl carboxylase

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2
Q

The name of Vitamin K obtained from the plant.

A

Phylloquinone or Vitamin K1

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3
Q

The name of Vitamin K obtained from intestinal bacteria.

A

Menaquinone or Vitamin K2

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4
Q

The synthetic form of Vitamin K

A

Menadione

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5
Q

Vitamin K food sources

A
Liver
Egg yolk
Cabbage
Spinach
Kale
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6
Q

Causes of Vitamin K deficiency

A
Poor diet
Gastrointestinal disorders
Neonate whose intestinal flora hasn't been established
Failure of liver to produce bile
Antibiotics
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7
Q

Vitamin K toxicity symptoms

A

Hemolytic Anemia

Jaundice

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8
Q

Enzyme Vitamin K epoxide reductase c1 reduces the vitamin k back to hydroquinone to continue the reaction. This enzyme is inhibited by which drug?

A

Warfarin

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9
Q

The principal role of vitamin K is in the posttranslational modification of a number of proteins most of which are involved in ___________ (transportation/clotting)

A

clotting

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10
Q

By using antibiotics like cefamandole, the bacterial population is affected causing vitamin k deficiency leading to _____________ (hypoprothrominemia/anemia)

A

hypoprthrombinemia

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11
Q

It is recommended that all newborns receive an intramuscular dose of vitamin k as prophylaxis to prevent __________________ because newborns lack intestinal flora.

A

hemorrhagic disease of the newborn

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