Vitamin B1 (Thiamine)

Question 1

Active form of vitamin B1 is ___________ (thiamine pyrophosphate/thiamine monophosphate)

Answer 1

thiamine pyrophosphate

Question 2

TPP is involved in ______________ (oxidative decarboxylation/deamination) and transketolase reactions.

Answer 2

oxidative decarboxylation

Question 3

Three enzymes have vitamin b1 as a coenzyme. What are the names of these enzymes?

Answer 3

Pyruvate dehydrogenase
Alpha-ketoglutarate dehydrogenase
Transketolase

Question 4

TPP is required in the ____________ (carboxylation/conjugation with CoA) step done by the dehydrogenase enzyme.

Answer 4

carboxylation

Question 5

Thiamine deficiency causes _____________ (beri beri/pellagra)

Answer 5

beri beri

Question 6

Dry beri beri involves _____________ (peripheral neuropathy/edema due to cardiomyopathy)

Answer 6

peripheral neuropathy

Question 7

Wet beri beri involves ___________ (peripheral neuropathy/edema due to cardiomyopathy)

Answer 7

edema due to cardiomyopathy

Question 8

Beri beri can lead to _____________ (Wernicke-Korsakoff syndrome/Horner syndrome)

Answer 8

Wernicke-korsakoff syndrome

Question 9

Mental confusion, Gait ataxia, nystagmus, and ophthalmoplegia are the symptoms of _______________ (Korsakoff syndrome/ Wernicke encephalopathy)

Answer 9

Wernicke encephalopathy

Question 10

Memory problems and hallucinations are the symptoms of __________________ (Korsakoff syndrome/ Wernicke encephalopathy)

Answer 10

Korsakoff syndrome