Vitamin K

Question 1

V-K types

Answer 1

• plants-phylloquinone-K1
• bacteria- menaquione- K2
• animal tissue= K1 +K2

Question 2

V-K absorption

Answer 2

-bile salts, pancreatic juice, CM form
-40-80% absorbed
transports from CM to liver
-stored in adrenal glands, lungs, bone marrow, lymph nodes

Question 3

V-K functions

Answer 3

• blood clotting- necessary for coagulation
• fibrinogen to fibrin by thrombin
• thrombin circulates in blood as prothrombin
• anticoagulation:
• -Warfarin
• -used to treat sclerosis
• -increase amounts of Warfarin resistance
• bone formation

Question 4

V-K AI

Answer 4

• 120 ug/d male

- 90 ug/d female

Question 5

V-K deficiency

Answer 5

rare

Question 6

V-K population at risk

Answer 6

• new born infant
• chronic use of antibiotics
• malabsorption of fat:
• • steatorrhea
• -pancreatitis
• -liver disease

Question 7

V-K toxicity

Answer 7

only with menadione

Question 8

V-K nutrition assessment

Answer 8

• measurement of prothrombin time:
• -time required for a fibrin clot to form
• -normal= 11-13 seconds
• ->25 seconds of hemorrhaging
• plasma prothrombin- 80-120 ug/mL