Vitamin K

Question 1

Most important role of vitamin K

Answer 1

• Clotting factors 2,7,9,10 require vitamin K for their activation
• they are activated by undergoing post translational modification with the help of vitamin K.
• which serve as a coenzyme in the reaction where the glutamic acid residues present in these proteins undergo carboxylation to form gamma carboxyglutamic acid

Question 2

Deficiency manifestation

Answer 2

• prolonged coagulation and bleeding

- newborns mostly pre term infants

Question 3

RDA

Answer 3

70-140 mewg/day