Vitamin B6 Flashcards
1
Q
Aka
A
Pyridoxine
2
Q
Active form
A
Pyridoxyl phosphate - PLP
3
Q
Biochemical functions
A
Heme synthesis Transamination Decarboxylation Production of niacin compounds Metabolism of sulphur containing amino acids Deamination
4
Q
Decarboxylation function
A
Histadine———–histamine
Tryptophan———hydroxytryptamine(serotonin)
Tyrosine——–dopamine, epinephrine, norepinephrine
Glutamate—–GABA
5
Q
Deficiency manifestation
A
HEMATOLOGICAL manifestations :microcytic hypochromic anemia….Hb synthesis is reduced
Hyperhimocystinemi
CARPAL TUNNEL SYNDROME
NEUROLOGICAL - irritability, general weakness, peripheral neuropathy, confusion, depression— occurs due to impaired synthesis of serotonin, GABA, catecholamines.
DERMATOLOGICAL - Sebarrheic dermatitis, stomatitis,glossitis,cheilosis.
Pellagra like symptoms
