Vitamin D Flashcards
What is the Vitamin D deficiency disease?
-Rickets
What is the active form of Vitamin D?
-Calcitriol (1alpha,25 dihydroxycholecalciferol)
What is the plant derived form of Vitamin D?
-D2(ergocalciferol)(not active form)
What is the form of vitamin D that is synthesized from sunlight and skin and found in animal sources?
-Cholecalciferol or Vitamin D3 (not active form)
What is the DRI for Vitamin D ages 1-70 for both male and females?
-600 IU (15mcg)
Give examples of food sources of vitamin D?
-salmon, fortified cereal, fortified milk, egg yolk, irradiated mushrooms
What is the upper level of Vitamin D?
-4,000 IU
-symptoms include nausea, vomiting, weakness and altered level of consciousness, excessive thirst
What are some of the factors that affect the body’s ability to synthesize vitamin D?
-Clothing and sunscreen, higher melanin content, skin temperature, burn patients,obesity and aging
Where is Vitamin D stored?
-Liver, adipose tissue, Pre-D3 in skin lipids
Where is Vitamin D excreted?
-bile, through feces
Bone formation is done by
-osteoblast
Bone resorption(breakdown of bone) is done by
-osteoclast
Describe what happens in the body when responding to hypercalcemia
-calcitonin levels increase
-osteoblasts build bone using calcium(take calcium from plasma to decrease levels)
-kidney increases calcium excretion
-feedback inhibition of 1 alpha hydroxylase to slow rate of active D formation