Vitamin Cofactors

Question 0

B2- Riboflavin

Answer 0

1: Complex II in electron transport chain
2: Succinate dehydrogenase: Succinate to Fumarate

Question 1

B1- Thiamin Pyrophosphate (TPP)

Hint: there are four

Answer 1

1: alpha ketoglutarate dehydrogenase (AKG to Succinyl CoA)
2: alpha ketoacid dehydrogenase: oxidative decarboxylation of BCAA
3: Pyruvate dehydrogenase: Pyruvate to Acetyl CoA
4: Tranketolase: Pentose Pathway

Question 2

Niacin

Answer 2

1: Malic enzyme: Malate & NAD to Pyruvate & NADPH (FA synthesis)
2: Malate Dehydrogenase: Malate & NAD to Oxylaloacetate & NADH
3: alpha ketoglutarate dehydrogenase:AKG to Succinyl CoA
4: GAPDH: GAP & NAD to 1,3-Bisphosphoglycerate & NADH (Glycolysis)

Question 3

B5: Pantothymic acid (CoA)

Answer 3

1: Fatty Acid Synthesis
2: Pyruvate Dehydrogenase Complex: Pyruvate to AcetylCoA
3: alphaketoglutarate dehydrogenase complex: AKG to Succinyl CoA
4: glutamate dehydrogenase: alpha-kg to glutamate

Question 4

B6: Pyridoxyl Phosphate

Answer 4

1: Transamination: OAA & glutamate to Aspartate & alpha ketoglutarate
2: Deamination: serine to Pyruvate & NH3
3: Glycogen phosphorylase: glycogen to glucose-1-phosphate

Question 5

B12: Cobalamin

Answer 5

Methylmalonyl CoA mutase: Methylmalonyl CoA to Succinyl CoA

Question 6

Biotin

Answer 6

1: Pyruvate Carboxylase: Pyruvate to OAA (glucogneogenesis)
2: Propionyl CoA Carboxylase: Propionyl CoA to Methylmalonyl CoA (odd chain FA into TCA cycle)
3: Acetyl Carboxylase: Acetyl CoA to Malonyl CoA (FA synthesis)

Question 7

Lipoid acid

Answer 7

1: Pyruvate Dehydrogenase: Pyruvate to Acetyl CoA
2: Alphaketoglutarate dehydrogenase: AKG to Succinyl CoA