Vit K Flashcards
1
Q
Types
A
plants-phylloquinone -K1
bacteria- menaquinone -K2
animal tissue-k1+k2
2
Q
Functions
A
blood clotting-necessary for coagulation
fibrinogen-> fibrin by thrombin
-thrombin circulated in blood as prothrombin
anticoagulants-Warfarin
-used to treat sclerosis
-increased amounts of Warfarin resistance
bone formation
3
Q
AI
A
120 mcg/d males
90 mcg/females
4
Q
Deficiency
A
Rare
5
Q
Population at risk
A
new born infants chronic use of antibiotic malabsorption of fat- -steatorrhea -pancreatitis -liver disease
6
Q
Tox
A
only w/menadione
7
Q
Nutrition Assessment
A
measurement of protrombin time *time required for fibrin clot to form * normal =11-13 seconds *>25 sec. hemmorrages plasma prothrombin- 80-120mcg/ml
8
Q
Absorption
A
bile salts, pancreatic juice, CM form
40-80% absorption
transport from CM–> liver
stored in adrenal glands, lungs, bone marrow, lymph nodes
9
Q
Bone Formation
A
- Osteoclastin-deposite to bone
- -Vit.K dependent protein
- -found in bone
- -secreted by osteoblasts-bone forming
