Visual Cortex Flashcards
If light falling on a region of the retina causes a decrease in the response of a ganglion cell – what type of region is this?
Inhibitory region
If a spot of light falls outside the receptive field of a ganglion cell what firing rate will be produced?
Baseline firing rate
Why do receptive fields increase in size with eccentricity (distance from the fovea)?
More rods are in the periphery and rods have more neural convergence
What kind of stimuli are ganglion cells good at detecting?
Change in the pattern of light
Spots of light or edges of light and dark
Define a receptive field
A region of the retina which, when stimulated by light, affects the firing rate of the cell
A region of the retina which, when stimulated by light, affects the firing rate of the cell
This is known as…?
Receptive field
Ganglion cell receptive fields have ……….. organisation
Centre-surround organisation
Ganglion cell receptive fields have centre-surround organisation. What are they?
1) ON-centre, OFF-surround
2) OFF-centre, ON-surround
What do retinal ganglion cells detect?
Spots of light and edges between areas of light and dark falling within the receptive field
Ganglion cell fibres leave the retina along the…?
Optic nerve
Detects spots of light and edges between areas of light and dark falling within the receptive field
Which cell does this?
Retinal ganglion cell
How is the optic nerve formed?
Ganglions have really long axons
The axons bundle together to form the optic nerve
The information then leaves the eye and travels up toward the brain
Define optic chiasm
Cross over point
What is the purpose of the optic chiasm?
Allows visual information to be represented as where in the world is the information coming from rather than from which eye does the information come from
Why is there a cross-over point (optic chiasm)?
The brain is reorganising how its going to represent and process visual information
How many optic nerves are there? And what are their roles?
There are 2
1) Left = processes info from the left eye
2) Right = processes info from the right eye
In the optic chiasm, do all fibres cross over?
No, some fibres cross over and some don’t
The cross-over point in the eye is called…?
Optic chiasm
Beyond the optic chiasm is called…?
Optic tract
What happens in the optic tract?
The info is now represented in terms of where in the world that info is coming from rather than which eye is it coming from
At the cross-over point (optic chiasm) what happens to the information seen in the left eye about the right side of the world?
The info falls on the left side of the retina and remains on the left side even at the optic tract
At the cross-over point (optic chiasm) what happens to the information seen in the left eye about the left side of the world?
The info falls on the right side of the retina and crosses over to the right side at the optic tract
At the cross-over point (optic chiasm) what happens to the information seen in the right eye about the left side of the world?
The info falls on the right side of the retina and remains on the right side even at the optic tract
At the cross-over point (optic chiasm) what happens to the information seen in the right eye about the right side of the world?
The info falls on the left side of the retina and crosses over to the left side at the optic tract
What does the left optic tract process?
Information coming from the right hand side of the world
What does the right optic tract process?
Information coming from the left hand side of the world
What happens to info at the optic tract?
Information is now separated by visual field rather than by eye
At the optic tract, information from the right visual field is represented …… hemisphere?
Left
At the optic tract, information from the left visual field is represented …… hemisphere?
Right
Where does the optic tract feed into?
Lateral Geniculate Nucleus (LGN)
Define LGN
It is a bilateral structure (one in the left hemisphere and one in the right)
Beyond optic chiasm the optic nerve becomes…?
Optic tract
What does the LGN do?
Each LGN receives input from the left and right eyes but keeps these inputs separate
What kind of receptive fields does the LGN have?
Centre-surround antagonism (the same receptive field organisation as retinal ganglion cells)
The receptive fields for LGN are ideal for detecting…?
Detecting spots of light and edges
The receptive fields for LGN are not ideal for detecting…?
Detecting orientation of bars/ edges
What is V1?
The Primary visual cortex
Where is V1 located?
Occipital lobe (back of the brain; away from the eyes)
Where does V1 receive its input from?
LGN
What unique pattern does V1 have?
Stripes
V1 (or primary visual cortex) is also known as…?
Striate cortex - because it is stripey
What is the physiological approach to measuring cell activity?
Single-cell recording
What happens in single-cell recording in a V1 cell? List 3 things
1) Stimulus is presented to an animal
2) An electrode is inserted into a neuron (e.g. V1 cell) and measures the electrical activity of a SINGLE neuron
3) Record what stimuli make that particular neuron the most active by measuring the cell firing rate over time
Who ran multiple experiments investigating what stimulus activates the V1 cell?
Hubel and Weisel
Hubel and Weisel ran multiple experiments investigating what stimulus activates the V1 cell in what time period?
Lat 50s to early 60s
When you don’t present a stimulus to the V1 cell, what happens to the firing rate of the cell?
V1 cells fire at baseline level (low firing rate) with infrequent action potential
What did Hubel and Wiesel discover about the V1 cell in the 1950s?
In the 1950s, Hubel and Wiesel could not find a stimulus to excite the V1 cell
They were aware that ganglion cells can be activated by spots of light and tried the same stimuli on V1
V1 was not triggered by spots of light
In the 1960s, what did Hubel and Wiesel discover about V1 cells?
Rectangular glass slides were put into the projector slot so the line passing over the retina made V1 fire
They found a big response from V1 when the edge of the slide moved across the receptive field
From this, they realised V1 cells like lines moving across the retina instead of spots
True or False
V1 cells like spots instead of lines moving across the retina
False
V1 cells like lines moving across the retina instead of spots
What is it called when a cell prefers lines of a particular orientation?
Orientation selectivity
Define orientation selectivity
When a cell prefers lines of a particular orientation
What makes V1 cells active?
Lines of light
What do V1 cells prefer?
Lines of light of a particular orientation
According to orientation selectivity, V1 cells perform best when…?
They encounter a stimulus of their preferred line orientation
e.g. a V1 cell likes horizontal lines and therefore will only respond strongly (high firing rate) when a horizontal line of light is presented
What is it called when objects close together in the visual scene are analysed by neighbouring parts of V1?
Retinotopic mapping
Define retinotopic mapping
When objects close together in the visual scene are analysed by neighbouring parts of V1
Simply = When cells in V1 that are close together process bits of the stimulus that are close together
When cells in V1 that are close together process bits of the stimulus that are close together
This is known as…?
Retinotopic mapping
True or False?
V1 is a structure that forms a map of the image that is falling on the retina
True
The amount of cortex devoted to representing each part of the retinal field is called?
Simply= How many neurons in an area of the visual cortex are ‘responsible’ for processing a stimulus of a given size
Cortical magnification
Define cortical magnification
The amount of cortex devoted to representing each part of the retinal field is distorted
Simply = How many neurons in an area of the visual cortex are ‘responsible’ for processing a stimulus of a given size
The amount of the cortex that is devoted to representing each bit of the stimulus
This is known as…?
Cortical magnification
Why is the amount of cortex devoted to representing each part of the retinal field distorted?
Bits of the image falling on the fovea get more of the cortex to process it
The fovea is represented by a large area of…?
Cortex
Fovea accounts for …… of the retina but is represented by ……… of V1
Fovea accounts for 0.01% of the retina but is represented by 8- 10% of V1
A stimulus that is closest to the fovea appears larger because…?
There’s a huge amount of cortex of V1 that’s devoted to processing bits of the stimulus closest to the fovea
A stimulus that falls into the peripheral appears smaller because…?
There is far less of the cortex of V1 that’s devoted to processing bits of the stimulus that fall into the peripheral
True or False?
Orientation preferences of V1 cells arranged in a random way
False
Orientation preferences of V1 cells arranged in an ordered way
Orientation preferences of V1 cells arranged in an ordered way
This organisation was investigated by …? List 2 ways
1) Recording from an electrode penetrating the cortex perpendicular to the surface of a V1 chunk
2) Recording from an electrode penetrating the cortex at an angle to the surface of a V1 chunk
When electrodes are inserted perpendicular to the surface of the V1 chunk, all cells have …?
The same orientation preference (an orientation column)
All cells of the V1 chunk have the same orientation preference when the electrode is inserted…?
Perpendicularly
All cells of the V1 chunk have varied orientation preferences when the electrode is inserted…?
At an angle
When electrodes are inserted at an angle to the surface of the V1 chunk, the cells’ orientation preferences ….?
Vary systematically