Vision Flashcards
Describe general photoreceptors.
What are the two specific types?
Receptor cells in the retina that transduce light into action potentials
Rods and cones
What portion of the EM spectrum can the human eye detect?
380-760
Describe Rods
receptors that respond to low intensity light, such as at night
Cones
Photoreceptor that is sensitive to different light intensities. Responsible for color vision and high acuity vision. Daytime vision
What is the retina, where is it located?
The retina is neural tissue that contains photoreceptors. It is located on the inner surface of the posterior eye
Where is the fovea?
Function?
The fovea is located in the central region of the retina. It is made specifically of cones and is responsible for mediating most acute vision.
Optic Disk
Location of exit point from the retina for fibers of ganglion cells that make up optic nerve. Forms a blind spot that we dont perceive
What are photopigments?
special molecules imbedded in the membrane of rods and cones that is responsible for transduction of visual info.
What is the photopigment in rods?
rhodopsin.
What is the photopigment in cones?
three classes of cone opsins: the basis of color vision
What happens when light activates a rhodopsin molecule?
Retinaldehyde dissociates from opsin revealing an enzymatic site on the opsin molecule. Combines rapidly with many molecules of G protein transducin…. long cascade of events. Ultimately results in change in membrane potential that results in glutamate release
describe rod/cone photoreceptors at resting potential
They steadily release glutamate. Light always hyper-polarizes the photoreceptors
Bipolar cells response to glutamate differ. Why?
They have different receptors. Glutamate depolarizes one group of bipolar cells but hyper-polarizes another. Differ by receptive field.
How does light close sodium channels in photoreceptors?
Light causes rhodopsin and RETINAL to unbind. This allows opsin to combine rapidly with the G protein transducin. Transducin acts through an enzyme, phosphodiesterase (PDE) to turn cGMP into 5’GMP. cGMP holds sodium channels open. Therefore, as transducin and PDE turn cGMP into 5’ GMP, sodium channels close. This results in hyperpolarization
What is the relationship between light, glutamate, and off-center bipolar cells?
Off-Center bipolar cells are excited when light is turned off. It receives more glutamate which depolarizes the off center cells.