virus structure, classification, and reproduction Flashcards

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1
Q

virus

A

genetic element that cannot replicate independently of a living (host) cell

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2
Q

virion (virus particle)

A

extracellular form of a virus
- facilitate cell-cell and host-host transmission

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3
Q

replication/ reproduction of viruses

A

occurs only upon infection (entry into the host cell)

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4
Q

virulent infection

A

replicates and destroys host (lysis of host cell)
- activated by stress

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5
Q

lysogenic infection

A

host cell genetically altered because viral genome becomes part of the host genome

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6
Q

capsid

A

protein shell that surrounds the genome of a virion
- self-assembly or require a host cell for folding assistance

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7
Q

naked viruses

A

have no other layers

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8
Q

enveloped viruses

A

have an outer phospholipid bilayer and viral proteins

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9
Q

capsomere

A

individual proteins arranged in a precise and highly repetitive pattern around the nucleic acid making up the capsid

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10
Q

helical symmetry

A

rod shaped virus

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11
Q

icosahedral symmetry

A

spherical viruses

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12
Q

lysosome

A

allow nucleic acid entry and release new virions

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13
Q

neuraminidase

A

destroy glycoproteins and glycolipids
- allows liberation of viruses from cells

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14
Q

RNA replicase

A

RNA dependent RNA polymerase

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15
Q

Reverse transcriptase

A

RNA dependent DNA polymerase in retroviruses

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16
Q

prokarytic virus

A

only nucleic acid enters a cell

17
Q

eukaryotic virus

A

entire virion enters a cell

18
Q

phases of viral replication in a permissive (supportive) host

A

1) attachment of the virion
2) penetration of the virion
3) synthesis of viral nucleic acids and protein by host cell as redirected by virus
4) assembly of capsids and 4.5) packaging of viral genomes into new virions
5) release of mature virions from host cells

APSAPR
already preaching some asinine & problematic reforms
attachment, penetration, synthesis, assembly & packaging, release

19
Q

virus replication is a _____ step growth curve

A

one

20
Q

when does an increase happen on a one step growth curve

A

when cells burst

21
Q

virus life cycle: eclipse

A

genome replicated and proteins translated

22
Q

virus life cycle: maturation

A

packaging of nucleic acids in capsids

23
Q

virus life cycle: latent period

A

eclipse + maturation

24
Q

virus life cycle: release

A

cell lysis, budding, or excretion

25
Q

burst size

A

number of virions released per infected cell

26
Q

plaque assay

A

number of plaques (clear zones that develop on lawns of host cells where successful viral infection occurs)

27
Q

temperate virus

A

replicate their genome in tandem with host genome and without killing host

28
Q

how much of a virion enters the animal cell

A

all of it

29
Q

site of replication for animal viruses

A

nucleus

30
Q

DNA viruses replicate in the

A

nucleus

31
Q

RNA viruses replicate in the

A

cytoplasm

32
Q

retroviruses viruses replicate in the

A

nucleus

33
Q

transformation

A

conversion of normal cell into tumor cell

34
Q

CPE

A

any visible change in appearance of an infected cell

35
Q

most human tumors/cancers (are/are not) caused by viruses

A

NOT