virus structure, classification, and reproduction Flashcards
virus
genetic element that cannot replicate independently of a living (host) cell
virion (virus particle)
extracellular form of a virus
- facilitate cell-cell and host-host transmission
replication/ reproduction of viruses
occurs only upon infection (entry into the host cell)
virulent infection
replicates and destroys host (lysis of host cell)
- activated by stress
lysogenic infection
host cell genetically altered because viral genome becomes part of the host genome
capsid
protein shell that surrounds the genome of a virion
- self-assembly or require a host cell for folding assistance
naked viruses
have no other layers
enveloped viruses
have an outer phospholipid bilayer and viral proteins
capsomere
individual proteins arranged in a precise and highly repetitive pattern around the nucleic acid making up the capsid
helical symmetry
rod shaped virus
icosahedral symmetry
spherical viruses
lysosome
allow nucleic acid entry and release new virions
neuraminidase
destroy glycoproteins and glycolipids
- allows liberation of viruses from cells
RNA replicase
RNA dependent RNA polymerase
Reverse transcriptase
RNA dependent DNA polymerase in retroviruses
prokarytic virus
only nucleic acid enters a cell
eukaryotic virus
entire virion enters a cell
phases of viral replication in a permissive (supportive) host
1) attachment of the virion
2) penetration of the virion
3) synthesis of viral nucleic acids and protein by host cell as redirected by virus
4) assembly of capsids and 4.5) packaging of viral genomes into new virions
5) release of mature virions from host cells
APSAPR
already preaching some asinine & problematic reforms
attachment, penetration, synthesis, assembly & packaging, release
virus replication is a _____ step growth curve
one
when does an increase happen on a one step growth curve
when cells burst
virus life cycle: eclipse
genome replicated and proteins translated
virus life cycle: maturation
packaging of nucleic acids in capsids
virus life cycle: latent period
eclipse + maturation
virus life cycle: release
cell lysis, budding, or excretion
burst size
number of virions released per infected cell
plaque assay
number of plaques (clear zones that develop on lawns of host cells where successful viral infection occurs)
temperate virus
replicate their genome in tandem with host genome and without killing host
how much of a virion enters the animal cell
all of it
site of replication for animal viruses
nucleus
DNA viruses replicate in the
nucleus
RNA viruses replicate in the
cytoplasm
retroviruses viruses replicate in the
nucleus
transformation
conversion of normal cell into tumor cell
CPE
any visible change in appearance of an infected cell
most human tumors/cancers (are/are not) caused by viruses
NOT