Virus del papiloma humano Flashcards

1
Q

Transmisión:

A

Contacto sexual.

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2
Q

Forma de proliferación del VPH:

A

Provoca proliferación celular benigna al interferir con proteínas oncosupresoras (p53 y p105RB), llevando a la formación de verrugas.

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3
Q

Serotipos asociados a mucosas (oral) (laringe, boca, conjuntival)

A

6 y 11

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4
Q

Serotipos asociados a malignidad:

A
  • Principalmente: 16 y 18.
  • Otros: 11, 31, 33, 35, 42 y 44.
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5
Q

Factores de riesgo para contraer VPH:

A

Inicio de vida sexual temprano, numero de parejas sexuales, numero de parejas de las parejas, no usar preservativo (condon), no estar circuncidado, no vacunación.

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6
Q

Clínica de verrugas genitales:

A

Condilomas acuminados en epitelio escamoso de genitales y región perianal.

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7
Q

Diagnostico de lesiones intraepiteliales:

A

Diagnóstico mediante citología cervical (tinción de Papanicolaou).

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8
Q

Metodos de diagnostico de VPH:

A
  • alta sospecha eb pacientes con neoformaciones verrugosas en areas anogenitales.
  • Colposcopia/penescopia, citlogia exfoliativa (coilocitos), biopsia, PCR.
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9
Q

Tratamiento de Verrugas:

A
  • Podafilina al 0.5% (PL)
  • Imiquimod al 5%
  • Podofilotoxina al 0.5%
  • Otros: Crioterapia, exceresis quirrugica, interferón, acido tricloroacético al 80-90%.
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10
Q

Manejo de dispalsias cervicales en premenopausia con colposcopia satisfactoria:

A

Tratamiento conservador (criocirugía, electrocirugía, láser).

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11
Q

Manejo de dispalsias cervicales en posmenopausia con colposcopia insatisfactoria:

A
  • Conización y/o histerectomía extrafacial.
    • Control citologico C/6 meses.
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12
Q

Manejo de dispalsias cervicales en gestantes:

A

Vigilancia y tratamiento post-puerperio, descartar enf. neoplásica invasora.

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13
Q
A
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14
Q
A
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