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virus ADN Flashcards

1
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3
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What is the clinical presentation of Mouse Parvovirus (MPV, MVM)?

A

Absence of clinical signs. MVM is a self-limiting infection.

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4
Q

What are the key prevention strategies for Mouse Parvovirus (MPV, MVM)?

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Control of vermin, quarantine, irradiated or autoclaved food if possible, PCR testing of biological products before administration to mice.

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5
Q

What methods can be used for eradication of Mouse Parvovirus (MPV, MVM)?

A

Re-derivations by hysterectomy or embryo transfer.

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6
Q

What actions should be taken in case of Mouse Parvovirus (MPV, MVM) infection?

A

Depopulation and decontamination.

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7
Q

How does Mouse Parvovirus (MPV, MVM) interfere with research?

A

It can disrupt the immune system, so infected mice should not participate in immunology projects.

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8
Q

What is Chapparvovirus murin (MuCPV)?

A

A new virus that causes renal disease only reported in immunodeficient adult models

This virus is a recent discovery in the field of virology.

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9
Q

What is the clinical presentation of MuCPV?

A

Renal disease chez des modèles immunodéficients adultes that can lead to kidney failure with morbidity and mortality

The disease severity varies based on the host’s immune status.

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10
Q

What aspects of MuCPV are currently under study?

A

Prevention, treatment, and interference with ongoing research

Research is critical to understand the virus’s impact and develop effective strategies.

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11
Q

True or False: MuCPV has been reported in healthy adults.

A

False

The virus is specifically linked to immunodeficient adult models.

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12
Q

Fill in the blank: MuCPV can lead to _______ with significant health consequences.

A

kidney failure

Kidney failure can result in severe health issues and complications.

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13
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14
Q

What are the clinical signs associated with natural infection of parvovirus in naive rats?

A

Possible clinical signs include:
* Hémorragies scrotales
* ↓ Gras corporel
* Congestion des ganglions lymphatiques

These signs are specific to rats that have not been previously exposed to the virus.

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15
Q

What is a possible consequence of transplacental transmission of parvovirus in rats?

A

Infertility and fœtal resorption

This indicates that the virus can impact reproductive success in infected rats.

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16
Q

What is a key preventive measure against parvovirus in rats?

A

Control de vermine, quarantaine, test PCR des produits biologiques avant administration aux souris

These measures help prevent the spread of the virus in laboratory settings.

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17
Q

What are the methods for eradication of parvovirus in infected populations?

A

Redérivations par hystérectomie ou transfert d’embryons, dépopulation et décontamination

These methods aim to eliminate the virus from affected populations.

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18
Q

How does parvovirus du rat interfere with research?

A

Can affect the immune system and induce hépatocellulaire necrosis in animals with existing liver issues + affecte étude sur le développement fetal

This interference can compromise the validity of research findings.

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19
Q

What systems can be negatively affected by parvovirus infection during fetal development? (autre raison pourquoi interfère avec la recherche)

A

Various systems including:
* Système nerveux
* Système gastrointestinal
* Système lymphatique
* Système hématopoiétique
* Système reproducteur

The impact on these systems highlights the importance of preventing infection during critical developmental periods.

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20
Q

Ectromélie ( virus Pox) SC et phase

A
  • Inflammation et nécrose des extremités ( pattes, queue, oreilles)
  • 2 phases:
    -1e virémie et multiplication a/n rate, foie → nécroses en bandes hachurées à la rate
    -2e virémie a/n peau → lésions cutanées (hypertrophie du membre et nécrose s’en suit)
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21
Q

Qu’est-ce qu’un protozoaire?

A

Un protozoaire est un organisme unicellulaire qui peut occasionner des diarrhées.

Les protozoaires sont souvent associés à des infections intestinales chez les animaux.

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22
Q

Comment les protozoaires peuvent-ils être observés?

A

Ils peuvent être vus à l’histopathologie ou au frottis direct.

Ces méthodes permettent d’examiner les tissus ou les échantillons pour détecter la présence de protozoaires.

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23
Q

Donnez un exemple de protozoaire et son effet sur l’intestin.

A

Exemples: Cryptosporidium muris, Spironucleus muris, Giardia.

  • Cryptosporidium muris affecte les cryptes intestinales.
  • Giardia affecte l’apex des villosités.
24
Q

Les protozoaires sont-ils toujours symptomatiques chez les animaux?

A

Non, les animaux peuvent être porteurs asymptomatiques.

Cela signifie qu’ils peuvent transmettre le protozoaire sans montrer de symptômes.

25
Vrai ou Faux: Les protozoaires ne causent jamais de diarrhées.
Faux. ## Footnote Les protozoaires peuvent occasionner des diarrhées chez les animaux.
26
Comment on diagnose les nématodes suivantes: Syphacia sp. et aspicularis tetraptera ?
* Syphacia spp. : banana shaped eggs, cecal contents for adults, fecal exam not reliable * Aspicularis tetraptera: examen fecal, adulte dans le grand intestin, pas dans le cecum ( habituellement asymptomatique)
27
Comment fait on la différence entre les cestodes hymenolepis nana et Hymenolepis diminuta ?
* Nana = filaments polaires aux 2 extrémités et zoonose * Requiert un vecteur = rare en labo
28
,Que sont les parasites suivant: Radfordia affinis, Myocoptes musculinus, myobia musculi et comment les diagnostique t'on + traitement?
* Ectoparasites * Diagnostic: * Papier collant sur les plaies ( en périphérie) ou les zones d'alopécie + identification ou microscope optique ( mites ou oeufs adhérés sur poils) * Traitement: Ivermectin
29
Type de tumeurs de glande mammaires de la souris?
* Adénome ( fibroadénome), adénocarcinome
30
SC de tumeurs de la glande pituitaire chez les rats
* Incoordiation, tête penchée
31
Traitements dermatite
* Argile verte * Taille de griffes * Chlorhexidine/proviodine topique * Ivermectin (mites) * Vitamine E * Enlever la litière (remplacer par litière de papier)
32
Traitement pododermatite
* Changement de litière * Hydrothérapie * Argile verte topique * Bandage
33
What type of diet is recommended for mice with malocclusion?
Soft food options such as: * Croquettes mouillés * Diète en gel ## Footnote These diets help in easier consumption for mice with dental issues.
34
What should be done if a mouse is dehydrated upon discovery?
Provide hydration to the mouse ## Footnote Dehydration can complicate health issues, including malocclusion.
35
Are breeding mice typically kept within the same colony if they have malocclusion?
No, breeding mice will normally not be kept within the colony ## Footnote This is to maintain the health and genetics of the colony.
36
Fill in the blank: Mice with malocclusion require _______ food options for easier eating.
[soft]
37
What is the main concern for mice with malocclusion regarding their diet?
The need for food that is easy to eat ## Footnote This is crucial to ensure they can maintain nutrition despite dental issues.
38
What is the management approach for a prolapse rectal less than 2 mm?
Suivre la progression ## Footnote This means to monitor the condition without immediate intervention.
39
For a prolapse rectal measuring between 2 mm and 7 mm, what is the recommended treatment?
Repousser le tissu avec un coton-tige humide vers l’intérieur, colle chirurgicale sur l’anus ## Footnote This involves using a moist cotton swab to push the tissue back in and applying surgical glue to the anus.
40
What symptoms indicate a prolapse rectal greater than 7 mm?
Apparence rouge, noirâtre, saignements ## Footnote These symptoms may indicate severe complications and could lead to euthanasia.
41
True or False: A prolapse rectal of 2 mm requires immediate surgical intervention.
False ## Footnote This condition requires monitoring rather than immediate surgery.
42
Fill in the blank: For a prolapse rectal measuring _______ mm, apply surgical glue on the anus.
2-7 ## Footnote This treatment is specific for prolapse rectal in this size range.
43
Traitement abcès glande prépuciale
* Auto-limitant * Drainer au besoin
44
45
What is the treatment for conjunctivitis?
Lavage au salin, application d'onguent antibiotique TID. Traitement topique pour 3 jours allant jusqu’à 2 semaines. ## Footnote TID signifie trois fois par jour.
46
What is a possible treatment for severe cases of conjunctivitis?
Énucléation possible ## Footnote L'énucléation est l'ablation chirurgicale de l'œil.
47
How can one test for the presence of ulcers in the eye?
Tester avec fluorescéine ## Footnote La fluorescéine est un colorant utilisé pour détecter les ulcères cornéens.
48
What should be done if an ulcer is present?
Traitement laborieux ## Footnote Cela peut impliquer des soins médicaux intensifs et prolongés.
49
Quelle est une cause fréquente de tête penchée chez la souris et le rat ?
Otite bactérienne ( Pasteurella, Pseudeumonas, Mycoplasme)
50
Quelle est une autre cause fréquente de tête penchée chez la souris ?
Artérite des vaisseaux entourant les canaux semi-circulaires ## Footnote Cette condition affecte la circulation sanguine dans les zones critiques pour l'équilibre.
51
Quelle est une cause de tête penchée chez le rat ?
Néoplasie (tumeur de la glande pituitaire) ## Footnote Les tumeurs peuvent affecter l'équilibre et la posture.
52
Quel traitement peut être utilisé pour la tête penchée due à une otite bactérienne ?
Antibiotiques ## Footnote Le choix de l'antibiotique dépend de l'agent pathogène identifié.
53
Le traitement de la tête penchée dépend de _______.
[la cause] ## Footnote Il est crucial de diagnostiquer correctement la condition sous-jacente.
54
Quelle option peut être envisagée si le traitement n'est pas efficace ?
Euthanasie ## Footnote Cela peut être considéré dans les cas de souffrance inacceptable ou de maladies incurables.
55
Hydrocéphalie
* Pronostic sombre et euthanasie
56
Comment on traite. une dystocie?
* Calcium/oxytocine euthanasie si la condition perdure( + de 24h) * Césarienne

organisms (19 decks)

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