Virus Flashcards
Birnaviridae envelope?
None
Birnaviridae genome?
RNA
Birnaviridae shape
Icosahedral symmetry
Birnaviridae in environment?
Stable
Birnaviridae replication?
In cytoplasm
Most important Birnaviridae genera
Avibirnavirus and Aquabirnavirus
Most important Avibirnavirus virus
Infectious bursal disease virus
Infectious bursal disease virus causes
Infectious bursal disease in immature chicken
Most important Aquabirnavirus
Infectious pancreatic necrosis virus
Infectious pancreatic necrosis virus causes
Infectious pancreatic necrosis in salmonid fish
Infectious bursal disease also known as
Gumoro disease
Infectious bursal disease virus main pathway
Oral and respiratory
Infectious bursal disease targets in the body
B lymphocytes and their precursors in the bursa of Fabricius
The outcome of the infectious bursal disease
immunosuppression
The forms of the infectious bursal disease
clinical and subclinical
Diagnosis of clinical form of the infectious bursal disease
Swollen bursa of fabricius at post mortem inspection
Diagnosis of the subclinical form of the infectious bursal disease
Immunofluorescence: smear of the frozen cut section of the bursa of fabricius can have viral antigen
ELISA: macerated bursal tissue
Viral isolation: bursa, spleen, feces
Infectious pancreatic necrosis affects mainly
youg salmonid fish less than 6 months, adults can be carriers
Transmission of the infectious pancreatic necrosis
Horizontal by water, also vertical
Clinical signs of infectious pancreatic necrosis
Swollen abdomen, anorexy, darkening of the epidermis, corkscrew swimming pattern
Post-mortem lesions of infectious pancreatic necrosis
Pancreatic necrosis, thick mucus in the intestines
Diagnosis of the infectious pancreatic necrosis
ELISA, PCR, IFAT, virus culture, histopathological smears of pancreas
Prevention of the infectious pancreatic necrosis
High water quality
Low stocking density
No mixing of batches
Transcription of Birnaviridae
inside virion with viral polymerase
