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Micro III > Flaviviridae > Flashcards

Flaviviridae Flashcards

1
Q

Flaviviridae envelope

A

yes

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2
Q

Flaviviridae nucleocapsid

A

icosahedral

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3
Q

Flaviviridae in environment

A

labile

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4
Q

Flaviviridae replication

A

in cytoplsdm

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5
Q

Flaviviridae gets out of cell by

A

exoxytosis

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6
Q

Flaviviridae important genera

A

Flavivirus (zoonotic) and Pestivirus

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7
Q

Flavivirus includes

A

West nile virus

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8
Q

West nile virus transmission

A

by arthropod vector(mosquito and tick)
blood/meat from carcasses
unpasteurised milk

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9
Q

West nile virus causes

A

encephalitis of horses, birds, and humans

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10
Q

west nile virus clinical signs

A 
encephalomyelitis with clinical signs in horses:
anorexy
depression 
weakness
ataxia 
even coma and death in 30% of cases

birds:asymptomatic

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11
Q

West nile virus samples:

A

birds: any affected tisue
horses: brain, spinal cord, blood

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12
Q

West nile virus diagnosis

A

pcr, elisa, immunofluorescence, plaqcue reduction neutralisation test

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13
Q

important pestivirus

A

bovine viral diarhhea virus I ja II, border disease virus and classical swine fever virus

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14
Q

pestivirus virulence factors

A

3 envelope glycoproteins Erns (soluble ribonuclease), E and E2(which neutralises ab)

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15
Q

bovine viral diarrhea transmission

A

oronasal and transplacental

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16
Q

bovine viral diarrhea virus causes

A

immunosupression in calves
enteric and respiratory diseases
abortions and still births (if infection during early pregnancy, persistent infection may occur unlike if infection in late pregnancy, if infection in mid-pregnany, congenital defects may occur)

17
Q

bovine viral diarrhea clinical signs in adults

A

fever, letharhy, anorexia, nasal and ocular discharges, oral lesions, diarhhea,

18
Q

bovine viral diarhhea samples

A

blood, serum, spleen, lymph nodes, gi tract lesions, milk

19
Q

bovine viral diarrhea diagnosis

A

ab’s from blood and milk, pcr and elisa

Micro III (5 decks)

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