Virology Tutorial

Question 1

Why do DNA viruses mutate less frequently than RNA viruses?

Answer 1

DNA polymerases have proofreading function, whereas RNA polymerases do not

Question 2

What does the treatment of Hepatitis C consist of?

Answer 2

Sofosbuvir, Ledipasavir + Ribavirin

Question 3

8 yo boy w fever, headache, sore throat + mild cough, has been sick for 2-3 days. Has runny nose + mild conjunctivitis, temp 39C, pulse 110, BP 90/60 and RR 42/min. Pharynx red + some bright red spots with white centres on buccal mucosa. Chest is clear.

What is the diagnosis?

Answer 3

Measles

Will have rash within next 2-5 days

Question 4

Middle of December, 2yo boy bought to A&E. History: cold-like illness ~ 4 days, child is now wheezing + seriously SOB, has fast HR, temp 38C. CXR shows peribronchial thickening.

What is the diagnosis?

Answer 4

Bronchiolitis causes by respiratory syncytial virus

Question 5

Which hepatitis viruses can be spread by contaminated food + water?

Answer 5

Hep A & E

Question 6

For monitoring of Hep C treatment, what tests + materials are needed?

Answer 6

Blood plasma for quantitative PCR to determine virus load

Question 7

Which virus is commonly associated with hemorrhagic fever?

Answer 7

Dengue virus

Question 8

A previously healthy 35yo poultry farmer dies from sudden pneumonia. What is the most likely cause?

Answer 8

Avian influenza which = enzootic in birds