Virology deck 1

Question 1

Double stranded DNA virus

Answer 1

must locate to nucleus, use Host DNA poly and RNA poly and ribosome

Question 2

single stranded DNA virus

Answer 2

must locate to nucleus, use host DNA poly to make double stranded DNA and the use host DNA poly to make single stranded DNA, use host RNA poly and ribosome

Question 3

double stranded RNA virus

Answer 3

replicates in cytoplasm, uses VIRAL RNA poly/replicase to make double stranded DNA, uses VIRAL poly/transcriptase to make single stranded and HOST ribosome

Question 4

single stranded RNA (-) virus

Answer 4

replicates in cytoplasm, uses VIRAL poly/transcriptase to make single stranded (+) mRNA, uses VIRAL replicase to make single stranded (-) mRNA genome from single stranded (+) mRNA, ribosomes use single stranded (+) mRNA

Question 5

single stranded RNA (+) virus

Answer 5

replicates in cytoplasm, uses VIRAL RNA poly/replicase twice, uses HOST ribosome

Question 6

RNA (+) retrovirus

Answer 6

repliactes nucleus to be incorporated into chromosomes, uses VIRAL reverse transcriptase to make negative single stranded DNA and to make double stranded DNA, VIRAL integrase, uses HOST RNA poly. uses HOST RNA poly to make viral mRNA and HOST ribosome

Question 7

Monocistronic

Answer 7

single large polypeptide synthesized, needs to be cut by viral protease into functional components

Question 8

polycistronic

Answer 8

viral mRNA with multiple genes translated into 1 or more polypeptides, proteases cleave these as well as to achieve separate functional units

Question 9

Virus assembly

Answer 9

capsids are assembled around the genome, envelopes acquired (if needed) during budding

Question 10

enveloping

Answer 10

matrix proteins for negative RNA strand viruses promote adhesion of nucleocapsid with the glyoprotein modified membrane

Question 11

capsid

Answer 11

protein shell that surrounds nucleic acid

Question 12

nucleocapsid

Answer 12

capsid + nucleic acid

Question 13

envelope

Answer 13

modified host cell membrane that wraps around nucleocapsid. proteins on envelope are viral proteins

Question 14

Naked virus

Answer 14

only capsid, stable to environment factors, survive long term both in body and outside the body, are more serious

Question 15

Enveloped viruses

Answer 15

have membrane that obtained from host cell membrane, can only survive in wet environments, are susceptible to acid, detergents, drying and heat, if enveloped damaged can no longer infect

Question 16

negative RNA viruses are

Answer 16

ENVELOPED

Question 17

viral replication process

Answer 17

target cell recognition and attachment, penetrating and uncoating, macromolecular synthesis, assembly of virus, budding of enveloped viruses and release