Virology Flashcards
6 DNA viruses
Enveloped
Herpes
Hep B
Smallpox
Naked
Parvo
Adeno
Papilloma
Papovavirus is now divided into
Papilloma
Polyoma
Naked RNA viruses
nO envelope
enterO: coxsackie, hav, echo, polio
rhinO
reO
H&A
Influenze, hemagglutinin and neuraminidase
MCC of common colds
Rhinovirus
The only DNA hepatitis virus
HBV
Progressive multifocal leukoencephalopathy
JK virus
JK virus family
Papova
Filoviruses
Ebola
Marburg
(hemorrhagic fevers)
Animals associated with MERSCoV
Camels
Earliest evidence of smallpox
Pustule on nose of mummified body of Pharaoh Ramses V
Tzanck smear
HSV, VZV
Flu-like symptoms in a patient with history of travel
Ebola
Ebola, biosafety level
4
MTb biosafety level
3
Ebola spp found in Philippines
Reston
Species where Reston was discovered
Monkeys (Cynomolgus macaques)
Most severe Ebola outbreak in history
Guinea, March 2014
Places traveled placed under alert level 2 in Phils
Guinea
Liberia
Sierra Leone
Cowdry Type A inclusions
HSV
Infectious mononucleosis
EBV
Cancers assoc with EBV
NPCA
Burkittโs lymphoma (Non Hodgkin)
Monospot test
EBV, detection of heterophile antibodies
Owlโs eye intranuclear inclusions
CMV
Roseola
HHV6
Atypical lymphocytes
EBV
Castleman disease
HHV8
Exanthem subitum
HHV6
In roseola, high fever lyses by ___ day
3rd-5th
Kaposi sarcoma
HHV8
Plantar warts, serotype
HPV 1,2,4,63
Aplastic crisis in sickle cell anemia
Parvovirus B19
Hepa: Fecal-oral route
A, E
Hepa: Sexual transmission
B, C
MCC post-transfusion hepatitis
C
Fifth disease
Parvovirus B19
Hepa: Dane particle
Infectious particle of Hep B
Hepa: No carrier state
Hep A
Hepa: First serologic marker detected
HBsAg
Slapped cheek
Parvovirus B19
Management for Hep B+ pregnant patient
Give Hep B Ig to baby within 12 hrs from birth
Hepa: Carrier state, serologic marker
HBsAg
Introduced vaccination
Edward Jenner (1980); injected himself with live cowpox to control smallpox
Assoc with hydrops fetalis
Parvovirus B19
Control of smallpox by deliberate infection with mild forms of disease
Variolation
Cause of mild smallpox
Vaccinia
Cause of severe smallpox
Variola
Presence of disease in more than the number of expected cases
Epidemic
Crisscross pattern
Parapox-/poxvirus
Paul-Bunnel test
EBV (aka monospot test)
MC viral infection after a renal transplant
CMV
Herpangina
Coxsackie A
DOC for HCV
Ribavirin
Hepa, serology: Acute infection
HBsAg
HBeAg
HBV DNA
Anti HBc IgM
Hepa, serology: Window period
Anti HBc IgM
Hepa, serology: Prior infection
Anti HBs IgG
Anti HBc IgG
Hepa, serology: Chronic infection
All markers of acute infection + Anti HBc IgG
Hepa, incubation periods: A
15-45 days
Hepa, incubation periods: B
50-180 days
Hepa, incubation periods: C
8 weeks
Hepa, incubation periods: D
40-180 days
Hepa, incubation periods: E
45 days
Echovirus, dse
Aseptic meningitis
Treatment for Coxsackie A
Supportive
Pleurodynia
Coxsackie B
Family: HCV
Flavi
Colorado tick fever
Reo
Very painful blisters on hands and feet
Coxsackie A
Bornholm disease
Coxsackie B
MCC of infantile diarrhea
Rota
Family: Yellow fever
Flavi
Family: Rota
Reo
Family: HEV
Calici
Family: Dengue
Flavi
Viral gastroenteritis
Rota
Norwalk
Family: St. Louis enceph
Flavi
Family: Norwalk
Calici
Family: Rubella
Toga
Family: West Nile enceph
Flavi
Family: Eastern and Western equine enceph
Toga
Family: Influenza
Orthomyxo
Family: Measles
Paramyxo
Family: Mumps
Paramyxo
Bronchiolitis
RSV
Croup
Parainfluenza
Lymphocytic choriomeningitis
Arena
Hantavirus from rodents
Bunya
3 Cโs
Measles
Negri bodies
Rabies
Kuru
Prion in cannibals
T/F The gland that mumps virus exclusively involves is the parotid
F, other glands also affected
Koplik spots
Measles
Babes nodules
Rabies
Hydrophobia in rabies is due to
Laryngospasm
Postauricular LAD
Measles
Common location of Koplik spots
Opposite 2nd upper molar tooth
MC prion disease affecting man
Creutzfeld Jacob
Case definition of mumps, swelling > ___ days
2, with no other apparent cause
Agent of Hecht pneumonia
Measles
Gertsmann-Straussier-Scheinker (GSS)
Prion
SSPE
Measles, complication
Spongiform encephalopathy
Creutzfeld Jacob
Virus that causes pancreatitis
Mumps
Congenital rubella is acquired at ___ trimester
1st
Heart dee assoc with congenital rubella
PDA
Rash of varicella classically begins at
Scalp/face/trunk
Characteristic of varicella lesions
Pruritic
Gold standard for diagnosis of rotavirus
Stool culture
MCC of rabies in the Phils
Dog bite
Herpesviruses
get herpes in a CHEVrolet CMV HSV EBV VZV
HSV that is an STD
HSV-2 (it takes 2 to tango)
Area of latency of VZV
Dorsal root ganglia
Multinucleated giant cells
Tzanck smear of HSV and VZV
Usual dermatome of shingles
Thoracic
Smallest infectious particle
Prion
Prion is made of
Protein
Scrapie
Prion infection in sheep
Mad cow disease
Prion
Dengue serotypes
1-4
Genotypes of dengue associated with severe disease accompanying secondary infection
2,3
Mosquito that breeds in clean water
Aedes
Mosquito that breeds in brackish water
Anopheles
Aedes bites during, day vs night
Day
Incubation period of dengue
4-10
Break-bone fever
Dengue
Phases of dengue
Febrile
Critical
Recovery
Rash described as isles of white in a sea of red
Herman rash (dengue)
Detection of NS1 Ag
Day 1 and Day 4 of illness
Hepa, serology: Acute Hep B
HBsAg
Anti HBc IgM
Hepa, serology: Chronic Hep B
HBsAg
Hepa, serology: Acute hep A superimposed on chronic hep B
HBsAg
Anti HAV IgM
Hepa, serology: Acute hep A and B
HBsAg
Anti HBc IgM
Anti HAV IgM
Hepa, serology: Acute hep A
Anti HAV IgM
Hepa, serology: Acute hep A and B, HBsAg below detection threshold
Anti HBc IgM
Anti HAV IgM
Hepa, serology: Acute hep B, HBsAg below detection threshold
Anti HBc IgM
Hepa, serology: Acute Hep C
Anti HCV