Virology Flashcards
Capsomeres, Lipoprotein Envelope
Capsid
2 Types of Capsid
Helical and Icosahedral
Nucleic acid genome + capsid
Nucleocapsid
All are enveloped
Helical
Can be enveloped or nake
Icosahedral
All DNA viruses are icosahedral except
Poxvirus
All RNA viruses are Helical Except
Hepeng Reo Picked Khaleesi Flavored Toga
Hepe Reo Pic Calici Flavi Toga
All RNA viruses are spherical except
Rhabdo Virus - Bullet Shaped
: interaction between nucleocapsid and envelope
Matrix Protein
• Lipid membrane derived from the host cells it is Acquired as the virus exits from the cell in a process called
Budding
Naked DNA Virus
Papa Perverted Ad caused Polio
Papiloma
Parvo
Adenovirus
Polyo
Naked RNA Virus
Reo Picked as Khaleesi’s Hepe
Reo
Pico
Calici
Hepe
Non Pathogenic prion protein config
Alpha Helix
Pathogenic prion protein config
Beta pleated
All viruses are haploid except
Retro Viruses
Segmented Genome Virus
BOAR Bunya Orthomyxo Arena Reo
RNA can immediately translated by the host’s ribosomes into protein
Positive stranded
brings its own RNA-dependent polymerase, which will carry out the transcription
Negative Stranded
ability to incorporate into the host genome
Retro virus
only RNA viruses with a double-stranded RNA genome
Reo viridae
Negative Strand RNA Virus
Always Bring Polymerase Or Fail Replication
Arena Bunya Paramyxo Ortho Filo Virus Rhabdo Virus
• Most DNA viruses have both a negative strand and a positive strand except
Parvo Virus
• All double-stranded DNA have icosahedral symmetry except
Pox
Single Stranded DNA
Parvo
refers to the DNA strand that is read; used as a template for transcription into mRNA
Negative Strand
crossing over within regions of significant base sequence homology
Recombination
viruses with segmented genomes exchange genetic material; causes epidemics
Genetic reassortment
one virus produces a protein that can be used by another virus
Complementation
two different viruses infect the same cell
Phenotype mixing
A single virus infects a cell
Entry
Virus decreases in number but continue to function
Decline
No virus is detectable inside the cell
Eclipse
Dramatic increase in amount of detectable viruses
Rise
Amount of detectable viruses reaches a plateau
Latenet
Marked derangement of cell function leading to lysis and cell death
Remarkable amplification in number of viral particles
Cytopathic effect
Oncogenic viruses induce transformation and unrestrained growth
Malignant transformation
Infected cells appear normal, but are producing large numbers of progeny viruses
Commensal symbiosis
Integrins (heparan sulfate)
CMV
CD21
EBV
CD4, CXCR4, CCR5
HIV
P antigen on RBCs
Parvovirus 19
Nicotinic AChR
Rabies
ICAM-1
Rhinovirus