Virology Flashcards
recombination
exchange of genes between 2 chromosomes
CROSSING OVER
Reassortment
viruses w/ SEGMENTED GENOMES exchange genetic material> pandemic
complementation
1 of 2 viruses that has a mutation needs another virus to make a functional protein
phenotypicmixing
infection of cell with TWO viruses
one virus can take on teh surface proteins of another virus to give it different tropism but it only lasts for one generation
Live attenuated vaccines
induce HUMORAL and CELL Immunity
Live! Only one night only. Small yellow rotating chieckens get vaccinated w/ Sabin and MMR. It’s INcreadible.
Small pox yellow fever rotavirus chicken pox Sabin (polio) MMR influenza intranasal
Killed vaccines
RIP Always
Rabies
Influenza
Salk Polio
HAV
Subunit vaccines
HBV
HPV
DNA viruses are all DS except…
parvo (too SMALL only room for ONE strand)
DNA are all LINEAR except….
papilloma
polyoma
hepadna
CIRCULAR
all RNA viruses are SS except…
reoviridae (DS)
+ RNA genomes
Retro toga flavi corona hepe calci pico
infectious purified nucleic acids
ds DNA
+ssRNA
Not infectious b/c they require POLYMERASES cotnained in complete virion
- strand (own viral transcriptase)
dsRNA (bring own polym)
DNA viruses replicate
NUCLEUS except POX (has its own DNA dep RNA pol)
RNA viruses replicate
CYTOPLASM
exxcept influenza nad tetro