Anti-bacterials Flashcards
Binds PBP
bocks transpeptidase cross linking
AUTOLYTIC
Pencilinc G
V
hypersensitivity rxns
hemolytic anemia
Peniciliinase that cleaves B lactam ring
Penicillin G, V
Combine w/ clavulanic acid
Wider spectrum than penicillin HHELPS
AmOxicillin–greater Oral bioavailability
Ampicillin
H. influ H. pylori E. coli L. monocytogenes Proteus Salmonella Shigella
hypersensitivity rxns
rash
pseudomembranous colitis
penicillinase
Amoxicilin
Penicilinase resistant b/c of BULKY R group
used for S. Aureus (except MRSA)
Naffcillin–NAF used for STAPH
dicloxacillin
oxacillin
Used for PSEUDOMONAS and Gram - rods
Piperacillin, ticarcillin (AKA anti-pseudomonals)
…hypersensitivity rxn
B lactamase inhibitors?
added to protect AB from penicillinase (B lactamase, periplasmin, plasmid coded)
CAST
clavulanic
ACID
Sulbactam
Tazoactam