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Microbiology > Virology > Flashcards

Virology Flashcards

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1
Q

Owl eye inclusions associated with

A

CMV

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1
Q

HIV Coreceptor in early infection

A

CCR5 on macrophage

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2
Q

Ebola is example of what type of virus

A

Filovirus

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2
Q

High fever, black vomitus, jaundice

eosinophilic apoptotic globules (Councilman bodies)

A

Yellow fever

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2
Q

CMV vs candida esophagitis findings:

A

CMV: linear ulcers

Candida: white plaques

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3
Q

Ulcerative gum lesions with intranuclear inclusions in child 1-3 yo

A

HSV-1

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4
Q

Generalized LAD including post-auricular and occipital in unvaccinated adult

A

Rubella

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5
Q

Virus that binds to CR2 or CD21

A

EBV

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6
Q

Rubella and equine encephalitis are examples of

A

Togavirus

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8
Q

HBV replication stages

A

dsDNA –> Template +RNA –> dsDNA

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8
Q

Supplementing which vitamin can reduce measles mortality in kids

A

A

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9
Q

Name 5 picornaviruses

A

PERCH

Poliovirus

Echovirus

Rhinovirus

Coxsackievirus

HAV

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10
Q

Naked (nonenveloped viruses):

A

Give **PAPP **smears and CPR to a naked Heppy

Papillomavirus

Adenovirus

Parvovirus

Polyomavirus

Calicivirus

Picornavirus

Reovirus

Hepevirus

PAPP = DNA

CPR & hepe = RNA

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10
Q

Viruses with segmented genome, thus enabling reassortment (name 2)

A

Rotavirus

Orthomyxovirus

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10
Q

HCV

Yellow Fever

Dengue

St. Louis encephalitis

West Nile virus

All are examples of?

A

Flavivirus

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11
Q

Lassa fever encephalitis and lymphocytic choriomeningitis virus are examples of what type of virus?

A

Arenavirus

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12
Q

Partially double stranded and circular

A

Hepadna

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13
Q

Blueberry muffin appearance suggestive of extramedullary hematopoiesis

A

Rubella

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13
Q

Parotitis

Orchitis

Meningitis

A

Mumps

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15
Q

Non-enveloped ssDNA

A

Parvovirus

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16
Q

Killed vaccines

A

Rabies

Influenza (injected)

Salk Polio

HAV

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17
Q

HIV coreceptor in late infection

A

CXCR4 on T cells

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18
Q

List the 7 DNA viruses

A

HHAPPPPy

Hepadna

Herpes

Adeno

Pox

Parvo

Papilloma

Polyoma

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19
Q

Virus that acquires envelop from cell nuclear membrane

A

Herpesviruses (including CMV)

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21
Q

Erythema infectiosum caused by

A

Parvovirus B19

22
Q

Most common global cause of infantile gastroenteritis

A

Rotavirus

22
Q

Function of gp41 in HIV

A

transmembrane – fusion and entry

24
Q

4 most common causes of viral meningitis

A

Coxsackie Virus

Echovirus

Poliovirus

Enterovirus

24
Q

hydrops fetalis associated with

A

parvo B19

26
Q

Which DNA viruses have ssDNA? dsDNA?

A

Everything has dsDNA except parvovirus

“part of a virus”

27
Q

Common adult rubella complication

A

Arthralgia

27
Q

Function of gp120 in HIV

A

docking – attachment to host CD4+ T cell

29
Q

JC virus and BK virus are in which viral family

A

Polyomavirus

31
Q

ssRNA w/ bullet shaped capsule studded with glycoprotein spikes

Binds to AChR

A

rabies

32
Q

function of pol in HIV

A

gene coding for reverse transcriptase, aspartate protease and integrase

33
Q

Anti-HAV IgM vs Anti-HAV IgG

A

IgM: acute hepatitis

IgG: prior infection and/or vaccination

34
Q

DNA virus that is not icosahedral, doesn’t replicate in nucleus

A

Pox

35
Q

CCR5 mutations

Homozygous:

Heterozygous:

A

Homozygous: immune to HIV

Heterozygous: slower course HIV

37
Q

Virus requiring HBsAg encapsulation

A

Hep D

38
Q

Bullet shaped virus

Negri bodies

Purkinje cells of cerebellum

Hippocampal neurons

A

Rabies

39
Q

Site of replication: DNA vs RNA virus

A

DNA: nucleus

RNA: cytosol

Beware of exceptions: poxvirus, influenza, retrovirus

FA pp 157

40
Q

CMV

Envelope?

Type of genetic material?

A

Enveloped

dsDNA

41
Q

Coltivirus and rotavirus are examples of

A

Reovirus

42
Q

Virus that binds to erythrocyte P antigen

A

Parvo B19

42
Q

Intranuclear and cytoplasmic inclusion bodies in immunocompromised patient

A

CMV

43
Q

function of p24 in HIV

A

capsid protein

44
Q

Sole positive marker of HBV infection during window period

A

Anti-HBc IgM

45
Q

Fecal-oral hepatidides

A

HAV and HEV

The vowels hit your bowels

47
Q

Name 4 segmented viruses

A

BOAR

Bunyavirus

Orthomyxovirus

Arenaviruses

Reovirus

48
Q

These naked nucleic acids are not infectious and require polymerases

A

dsRNA

negative ssRNA

50
Q

High fever for several days causing diffuse maculopapular rash

A

Roseola

51
Q

Incubation period in HDV

Superinfection:

Coinfection:

A

Superinfection: Short (poor prognosis)

Coinfection: Long

52
Q

3 circular RNA viruses

A

ABD

Arenavirus

Bunyavirus

Delta virus

54
Q

Surface fusion protein (F protein) are present in this family of viruses

A

Paramyxovirus

55
Q

Name 6 negative-stranded RNA viruses

A

Always Bring Polymerase Or Fail Replication

Arenavirus

Bunyavirus

Paramyxovirus

Orthomyxovirus

Filoviruses

Rhabdoviruses

56
Q

Koplik spots

Warthin-Finkeldey giant cells (fused lymphs)

Coryza

Conjunctivitis

A

Measles

57
Q

Mononucleosis-like symptoms but no heterophil antibodies

A

CMV

58
Q

In EBV, are atypical lymphocytes B cells or T cells? What type?

A

Cytotoxic T cells (not the infected B cells through CD21)

59
Q

All DNA viruses are linear except these are circular:

A

papilloma

polyoma

hepadnavirus

60
Q

Norovirus is example of

A

Calicivirus

61
Q

Only RNA virus that is double stranded

A

reovirus

62
Q

Positive stranded RNA viruses (name 7)

A

I went to a retro toga party where I drank flavored Corona and ate hippy California pickles

Retro

Toga

Flav

Corona

hepe

calici

picorna

Microbiology (5 decks)

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