VIROLOGY Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

A mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without envelope is called a:
A. Nucleocapsid
B. Genome
C. Virion
D. Capsomer

A

C. Virion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Viruses are characterized by the presence of:
A. Mitochondrial DNA
B. DNA and RNA
C. Ribosomal RNA
D. RNA

A

B. DNA and RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the largest DNA virus?
A. Herpesvirus
B. Poxvirus
C. Adenovirus
D. Parvovirus

A

B. Poxvirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which of the following is the smallest RNA virus?
A. Paramyxovirus
B. Togavirus
C. Rhabdovirus
D. Enterovirus

A

D. Enterovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the first step in the replication cycle of a virus?
A. Attachment and penetration
B. Assembly of a virion
C. Release
D. Uncoating

A

A. Attachment and penetration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The virus capsid morphology is:
A. Square or round
B. Long or short
C. Ribbon-like or square
D. Helical or icosahedral

A

D. Helical or icosahedral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

From what part of the virus is the envelope acquired?
A. Nuclear or cytoplasmic membrane
B. Nucleus or cytoplasm
C. Capsomeres or genomes
D. mRNA or DNA

A

A. Nuclear or cytoplasmic membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the site of virion assembly?
A. Capsomere
B. Nucleus or cytoplasm
C. Genomes
D. Membranes

A

B. Nucleus or cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which of the following is a DNA virus?
A. Retroviridae
B. Orthomyxoviridae
C. Herpesviridae
D. Paramyxoviridae

A

C. Herpesviridae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which of the following is a RNA virus?
A. Pseudomyxoviridae
B. Papoviridae
C. Herpesviridae
D. Poxviridae

A

A. Pseudomyxoviridae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Specimens collected for virus isolation should be kept at:
A. 37 C
B. 20 C
C. 4 C
D. -20 C

A

C. 4 C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

At what temperature should clinical specimens suspected of containing viruses kept for transport that takes days?
A. -70 C
B. 37 C
C. 4 C
D. -10 C

A

A. -70 C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In what family of viruses, after primary infection, does an individual become latently infected and then the infection can be reactivated?
A. Adenoviridae
B. Herpesviridae
C. Poxviridae
D. Papovaviridae

A

B. Herpesviridae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Cytomegalovirus isolation is best accomplished using:
A. Monkey kidney cells
B. A549 cells
C. Human embryonic fibroblasts
D. Embryonated hen’s eggs

A

C. Human embryonic fibroblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which of the following viruses causes acute central nervous system disease in humans and animals?
A. Rabies
B. Influenza
C. Mumps
D. Measles

A

A. Rabies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What specimen/s should be collected from a patient with suspected enteroviral meningitis?
A. Stool
B. Throat swab
C. Cerebrospinal fluid
D. AOTA

A

D. AOTA

17
Q

Influenza A viruses can be detected in cell cultures by:
A. Complement-fixation test
B. Hemadsorption assay
C. Immunoperoxidase test
D. Hemagglutination-inhibition test

A

B. Hemadsorption assay

18
Q

The best host systems for influenza virus isolation are:
A. Monkey kidney cells and embryonated hen’s eggs
B. Monkey kidney cells and human embryonic fibroblasts
C. Human embryonic fibroblasts and embryonated hen’s eggs
D. Monkey kidney cells and A549 cells

A

A. Monkey kidney cells and embryonated hen’s eggs

19
Q

What common antigen is cross-reactive in all human adenoviruses?
A. Fiber
B. Hexon
C. Hemagglutinin
D. Capsomere

A

B. Hexon

20
Q

The following characteristics are similar in both influenza and parainfluenza viruses, except:
A. Helical symmetry
B. Lipid envelope
C. Budding from cytoplasmic membrane
D. Segmented RNA genome

A

D. Segmented RNA genome

21
Q

Myxoviridae virus envelope contains both:
A. Neuraminidase and hemagglutinin
B. Lipoprotein and nonsegmented nucleocapsid
C. Lipid and double stranded DNA
D. Hemagglutinin and nonsegmented nucleocapsid

A

A. Neuraminidase and hemagglutinin

22
Q

Eosinophilic cytoplasmic inclusions are elementary bodies of the:
A. Herpesvirus
B. Poxvirus
C. Poliovirus
D. Papilloma virus

A

B. Poxvirus

23
Q

German measles is caused by:
A. Rubeola virus
B. Rubella virus
C. Varicella-zoster virus
D. Vaccinia virus

A

B. Rubella virus

24
Q

What is an alastrim infection?
A. Smallpox
B. Chickenpox
C. Mild form of smallpox
D. Measles

A

C. Mild form of smallpox

25
Q

Which of the following laboratory procedures is routinely used for the detection of hepatitis B virus (HBV) in blood donors?
A. Solid-phase RIA
B. ELISA
C. Culture
D. A and B

A

D. A and B

26
Q

Which of the following laboratory procedures is the most rapid method for diagnosis of a virus infection?
A. Culture
B. Serological tests
C. Direct electron microscopy
D. Cytopathic effect (CPE) in cell cultures

A

C. Direct electron microscopy

27
Q

What specimen/s should be collected from a patient with suspected influenza?
A. Stool
B. Throat swab
C. Urine
D. AOTA

A

B. Throat swab

28
Q

What virus group contains a double-stranded, segmented RNA genome?
A. Herpesvirus
B. Influenza virus
C. Parainfluenza virus
D. Reovirus

A

D. Reovirus

29
Q

Enteroviruses can be differentiated from rhinoviruses by:
A. Acid resistance
B. Size determination
C. Ether stability
D. Ribonuclease treatment

A

A. Acid resistance

30
Q

What virus is the most frequent cause of gastroenteritis in children during the winter months?
A. Influenza viruses
B. Adenoviruses
C. Rotavirus
D. Hepatitis A virus

A

C. Rotavirus

31
Q

All of the following groups of viruses are resistant to ether treatment, except:
A. Herpesviruses
B. Adenoviruses
C. Enteroviruses
D. Reoviruses

A

A. Herpesviruses

32
Q

The most common method for rapid electron microscopy examination is:
A. Negative staining
B. Acid-fast staining
C. Gram stain
D. Periodic Acid-Schiff stain

A

A. Negative staining

33
Q

Various virus groups can be differentiated in negatively stained specimens by their:
A. Envelope
B. Cytoplasmic membrane
C. Morphology
D. Nucleus

A

C. Morphology