Virology Flashcards

1
Q

What 2 clinical signs are associated with epitheliotropic viruses?

A

Diarrhea and ulcers

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2
Q

What 3 clinical signs are associated with endotheliotropic viruses?

A

Hemorrhage, edema, ischemia, and necrosis

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3
Q

Give 3 examples of Pestiviruses that cause diarrhea

A

BVD, Border disease, and Classical swine fever

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4
Q

Where does Rotavirus replicate?

A

Cytoplasm of mature enterocytes

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5
Q

Where is the portal of entry of Rotavirus in cattle?

A

Mouth

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6
Q

What age of cattle are most commonly affected by rotavirus?

A

Calves 1-2 weeks old

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7
Q

What are the gross or histologic lesions associated with rotavirus?

A

Most of the time there are none

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8
Q

What virus associated with high mortality in newborn piglets is an alphacoronavirus that is highly contagious and has clinical signs of vomiting and diarrhea?

A

Transmissible gastroenteritis virus

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9
Q

What virus is a betacoronavirus that is an important cause of calves 7-10 days old with diarrhea, especially in the winter months and with co-infection with other viruses and bacteria?

A

Bovine coronavirus

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10
Q

What type of inclusion bodies does Parvovirus form?

A

Intranuclear inclusion bodies

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11
Q

What is the target of parvovirus?

A

Crypts of epithelial cells

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12
Q

Transplacental infection of feline panleukopenia results in either?

A

Fetal death or cerebellar hypoplasia

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13
Q

Where is viral replication of feline panleukopenia?

A

Oropharynx and regional lymph nodes

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14
Q

What is the transmission of feline panleukopenia?

A

Ingestion or inhalation

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15
Q

What is the transmission of canine parvovirus?

A

Ingestion

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16
Q

Where is viral replication of canine parvovirus?

A

Oropharynx and Peyer’s patches

17
Q

What type of virus causes intestinal villous blunting and fusion with crypt necrosis?

A

Parvovirus

18
Q

What biotype of bovine viral diarrhea results in disease?

A

Non-cytopathic virus

19
Q

Do non-cytopathic or cytopathic virus biotypes of BVD result in PI animals?

A

Non-cytopathic

20
Q

What is the most common clinical form of BVD virus?

A

Abortion or birth defects (cerebellar hypoplasia)

21
Q

Acute BVD mucosal disease occurs when a PI animal is infected with a ___________ BVD strain at any point in life.

A

Cytopathic

22
Q

What 2 gross lesions are associated with acute BVD and mucosal disease?

A

Esophageal ulceration and necrosis of Peyer’s patches

23
Q

When testing a herd for BVD, which calves should be tested?

A

All of them (born dead or alive)

24
Q

How can you differentiate between Rinderpest and BVD?

A

Rinderpest has syncytia, BVD does not

25
Q

What morbillivirus has been eradicated in cattle and had clinical signs of fever, anorexia, oculonasal discharge, ulcers in mouth and tongue, and severe watery and bloody diarrhea?

A

Rinderpest

26
Q

What morbillivirus in dogs affects the respiratory, GI, and neurologic systems and can result in either acute disease followed by recovery and lifelong immunity or neurologic disease and death?

A

Canine Distemper Virus

27
Q

Old dog encephalitis can occur years after recovery of which virus and results in neurologic deterioration and death?

A

Canine Distemper Virus

28
Q

What is the primary target of infectious canine hepatitis caused by canine adenovirus 1?

A

Vascular and corneal endothelial cells

29
Q

If a dog with infectious canine hepatitis has a fever that persists for more than one day, what will happen?

A

Systemic illness usually occurs

30
Q

Why do we use canine adenovirus 2 in our vaccines against canine adenovirus 1?

A

We don’t use CAV-1 in our vaccines because they would shed the virus and infect other animals

31
Q

What type of inclusion bodies are seen with herpesvirus?

A

Intranuclear inclusion bodies

32
Q

What makes canine alpha herpesvirus different from other herpesviruses?

A

It is the only one that can replicate better in lower body temps

33
Q

You have performed necropsy on a neonatal puppy and found a ton of white specks all over the liver. What is a top differential based on the gross lesions?

A

Herpesvirus