Viral Skin Infections Lecture Powerpoint Flashcards

oof

You may prefer our related Brainscape-certified flashcards:
1
Q

Wart definition

A

Benign roliferation of skin and mucosa caused by HPV transmitted via direct or indirect contact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

HPV subtypes associated with malignancy (6)

A

6, 11, 16, 18, 31, 35

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Heck disease/focal epithelial hyperplasia

A

A rare manifestation of HPV of the oral mucosa with an infecetion of some subtypes of HPV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Common warts on the hands and feet are typically what subtype? (2)

A

2,4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Deep palmoplantar warts/myrmecia and what subtype causes it?

A

Sharp calloused warts that grow deep and are more painful than common warts, tend to occur in weight bearing areas, caused by subtype 1 predominantly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Butcher’s wart and what subtype causes it?

A

Cutaneous skin condition among butchers and other meat handlers caused by HPV subtype 7 that infects the skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Most warts spontaneously resolve within…

A

…2 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When should warts be treated? (4)

A

-if present for more than 2 years -if spreading or symptomatic -if psychosocial or employment ramifications -if concern for malignancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

First line of treatment for warts

A

Salicylic acid topical repeatedly (might supplement with adhesiotherapy as well)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cryotherapy

A

Use of liquid nitrogen in multiple treatment sessions to destroy a wart often done in conjugation with other treatments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Verruca vulgaris

A

Common wart, usually asymptomatic but painful at times and appears as a hyperkaratotic papule with rough irregular surface and often seen on hands and knees but can occur anywhere, resoves without intervention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Verruca plantaris

A

Plantar warts that typically manifest as small growths on sole of foot, may be painful, often occur at pressure points, typically treated if painful or spreading

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Filform (digitate) warts

A

Long slender growths with stalk like appearance that manifest on areas of thin skin (such as face) and commonly bleed, often need treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Some rare forms of warts or those that do not resolve are common feature of a ___ patient

A

HIV positive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Verruca planus

A

Flat warts that frequently appear on back of hands, shins, and face, appear as flesh colored flat topped papules and can become very confluent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Subungal and periungal warts

A

Warts that appear around or under the fingernail, more resistant due to barrier and painful to treat due to proximity to sensitive nail bed, laser therapy might be an option

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Whats the concern of untreated subungal or periungal warts?

A

Damage to nail matrix causes permanent and irreversible nail disfigurement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Genital warts (condylomata acuminata) are most often these 2 subtypes

A

6 and 11

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Condylomata acuminata

A

Genital warts, can be found in any area of sexual contact, can be asymptomatic or cause burning, itching, tenderness

20
Q

Concerns of pregnancy and genital warts

A

-Neonates may acquire infection when passing thru infected birth canal so depending on number of lesions may advise C section to avoid transmission to neonate

21
Q

2 biggest treatments for genital warts

A

-surgical excision (lowest recurrence rate) -cryotherapy (safe even during pregnancy)

22
Q

Molluscum contagiosum

A

Caused by a DNA poxvirus strictly in humans, has distinct appearance of single or multiple umbilicated (caseous plug, distinct clinical diagnosis) papular lesions round, dome shaped and waxy

23
Q

Majority of molloscum contagiosum infections are caused by type ___ poxvirus

A

1

24
Q

How is molluscum contagiosum spread? What are 3 distinct disease patterns prevalent?

A

-Direct contact or fomites -children (fomites), immunocompetent adults (STI), and immunocompromised children or adults (widespread)

25
Q

Both molluscum contagiosum and HPV can undergo spread to different parts of the body via…

A

…autoinoculation

26
Q

Molluscum contagiosum spares the ___ and ___ (most of the time)

A

palms, face

27
Q

Most effective treatment for molluscum contagiosum

A

Curettage, most of the time spontaneously resolves tho

28
Q

HSV 1 is typically presenting as ___ and HSV 2 as ____, but….

A

orofacial, genital, starting to see more and more crossover

29
Q

Herpes simplex virus

A

An infectious DNA virus of which humans are the only natural reservoir, invades NS and goes into latency until reactivation, spread via close personal contact, 90% of adults seropositive for HSV1 by 50’s and don’t realize it (very VERY common)

30
Q

HSV primary infection

A

Tends to be accompanied by systemic signs, sometimes not even manifesting lesions and thus aren’t diagnosed

31
Q

Herpes labialis

A

Herpes around the lips, most common recurrent HSV 1 infection

32
Q

Herpetic whitlow Herpes gladiatorum

A

-HSV of finger following inoculation from self or other -Face, arms, neck, and trunk infection from contact sport players

33
Q

HSV gold standard diagnositc test

A

Isolation of virus by culture

34
Q

Tzank smear

A

A quick rapid means of testing HSV but does not distinguish between 1 and 2

35
Q

A serologically negative patient but viral culture positive patient for HSV indicates the patient is undergoing…

A

…primary infection

36
Q

Treatments for HSV (4 of the same family and 1 fun fact about each(

A

-Pencyclovir (only topical prep) -Acyclovir (5 times a day dosing) -valancyclovir (better dosing) -famciclovir (better bioavailablilty)

37
Q

Varicella zoster virus causes these 2 infections with skin manifestations

A

Varicella (chicken pox, initial exposure) herpes zoster (shingles) reactivation of virus

38
Q

Characteristic rash of varicella zoster virus

A

“Dewdrop on roses” maculopapular lesions

39
Q

Herpes zoster appearance

A

Vesicular rash in a single dermatome that almost never crosses dermatomes and rarely crosses to multiple dermatomes

40
Q

Post herpatic neuralgia

A

Complication of herpes zoster that can last for years

41
Q

Herpes zoster opthalmicus

A

Reactivation of the herpes zoster virus in trigem nerve that can cause occular involvement

42
Q

Starting antiviral therapy within 72 hours of shingles outbreak…

A

…can limit risk of post herpatic nerualgia

43
Q

What condition is this?

A

Filiform wart

44
Q

What condition is this?

A

Molluscum contagiosum

45
Q
A