viral phases of lifecycle Flashcards
- adsoprtion
When a virus can invade its host cell only through making an exact fit with a specific host molecule
Host range in adsoprtion
1.
the limited range of cells that a virus can infect:
Hepatitis B: liver cells of humans
Poliovirus: intestinal and nerve cells of primates
Rabies: various cells of all mammals
Cells that lack compatible virus receptors are
1.
resistant to adsorption and invasion by that virus.
What is tropism?
1.
specificities of viruses for certain tissues
Step 2: Penetrating and uncoating Penetration through endocytosis happens when
an entire virus is engulfed by the cell and enclosed in a vacuole or vesicle.
Direct penetration;Step 2: Penetrating and uncoating
fusion of the viral envelope with the cell membrane
Step 2: Penetrating and uncoating
Enzymes in the vacuole dissolve the envelope and capsid.
Virus fuses with the wall of the vesicle.
Viral nucleic acid is released into the cytoplasm
uncoating
synthesis and replication part 3:
Enter the host cell’s nucleus and are replicated and assembled there
DNA viruses:
synthesis and replication part 3: : replicated and assembled in the cytoplasm
RNA
synthesis and replication part 3: turn their RNA genomes into DNA.
Retroviruses
Assembly and release: part 4: virus is put together using “parts” manufactured during the synthesis process.
Assembly:
Assembly and release: part 4:
the number of viruses released by infected cells is variable, controlled by:
Size of the virus
Health of the host cell
Release
The flexible cell membrane of the host is penetrated by the whole virus or its nucleic acid.: True or false?
Step 2
true